Announcements Trials
Browse Landscape

Phase

Phase 3 2Phase 2 1Phase 1 1

Status

Completed 4

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Head & Neck 4Thoracic 1Gynecologic 1Genitourinary 1

Conditions

Parkinson Disease 4, Autosomal Dominant Lewy Body 15Neoplasms 10Carcinoma, Renal Cell 8Carcinoma, Hepatocellular 8Melanoma 7Carcinoma, Non-Small-Cell Lung 7Endometrial Neoplasms 6Thyroid Neoplasms 5Squamous Cell Carcinoma of Head and Neck 4Recurrence 4Thyroid Cancer, Papillary 3Stomach Neoplasms 3Neuroendocrine Tumors 3Colorectal Neoplasms 3Adenocarcinoma, Follicular 3Ovarian Neoplasms 2Osteosarcoma 2Neoplasm Metastasis 2Lymphoma 2Lung Neoplasms 2Glioma 2Carcinoma, Transitional Cell 2Carcinoma 2Biliary Tract Neoplasms 2Uveal Melanoma 1Triple Negative Breast Neoplasms 1Thyroid cancer, medullary 1Thyroid cancer, Hurthle cell 1Thyroid Diseases 1Thyroid Carcinoma, Anaplastic 1

Interventions

Cisplatin 76Cetuximab 60pembrolizumab 56Radiotherapy, Intensity-Modulated 37Radiotherapy 33Carboplatin 31Docetaxel 30Fluorouracil 27Nivolumab 26Paclitaxel 20Platinum 10Albumin-Bound Paclitaxel 9Surgical Procedures, Operative 8Radiosurgery 8Radiation 8Erlotinib Hydrochloride 8durvalumab 7Bevacizumab 71,2-diaminocyclohexaneplatinum II citrate 7epacadostat 6Biopsy 6Radiotherapy, Conformal 5Ipilimumab 5Immunoglobulin G 5Gemcitabine 5Capecitabine 5130-nm albumin-bound paclitaxel 5utomilumab 4tremelimumab 4palbociclib 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Has results × Squamous Cell Carcinoma of Head and Neck × lenvatinib × Clear all
NCT04199104 2026-05-05

A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010) (KEYNOTE-010)

Merck Sharp & Dohme LLC

Phase 3 Completed
511 enrolled 20 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05523323 2026-03-13

A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010/LEAP-010)-China Extension

Merck Sharp & Dohme LLC

Phase 3 Completed
112 enrolled 16 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04428151 2025-12-04

LEAP-009

Merck Sharp & Dohme LLC

Phase 2 Completed
408 enrolled 17 charts
Head & Neck

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck

NCT03006887 2021-05-20

Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid Tumors

Eisai Inc.

Phase 1 Completed
6 enrolled 27 charts
GenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Endometrial Neoplasms

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