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Phase

Phase EARLY_PHASE1 1Phase 1/2 1

Status

Withdrawn 2Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2

Conditions

Squamous Cell Carcinoma of Head and Neck 2

Interventions

Cisplatin 14pembrolizumab 8Radiotherapy 7Nivolumab 7Radiotherapy, Intensity-Modulated 5Cetuximab 5Carboplatin 5Fluorouracil 4durvalumab 3Radiosurgery 3Magnetic Resonance Spectroscopy 3Docetaxel 3fluoromisonidazole 2epacadostat 2Standard of Care 2Specimen Handling 2Photochemotherapy 2Paclitaxel 2Drug Therapy 2Cyclophosphamide 2Chemotherapy, Adjuvant 2Capecitabine 2C188-9 compound 2zimberelimab 1yeast-CEA vaccine 1vandetanib 1temoporfin 1talazoparib 1ruxolitinib 1olaparib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Withdrawn × Squamous Cell Carcinoma of Head and Neck × C188-9 compound × Clear all
NCT05668949 2025-12-17

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

M.D. Anderson Cancer Center

Phase 1/2 Withdrawn
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05845307 2025-12-08

Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Withdrawn
Head & Neck

Squamous Cell Carcinoma of Head and Neck

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