Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck × Chemoradiotherapy × Clear all

NCT07601737 2026-05-22

Nimotuzumab Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase 2 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05526924 2026-03-04

Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer

Phase 1 Recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07407205 2026-02-17

Tumor Mutational Burden, Liquid Biopsy, Angiogenic Factors and DCE-MRI Perfusion in HPV-Negative Oropharyngeal Cancer

Phase NA Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Oropharyngeal Neoplasms

NCT05894083 2026-02-02

A Phase II Study for p16+ Oropharyngeal Cancer PerSonalized De-escalation Treatment at University of MIchigan (CuSToMIze)

Phase 2 Recruiting

Squamous Cell Carcinoma of Head and Neck, Oropharyngeal Neoplasms

NCT07371611 2026-01-28

Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma

Phase 3 Recruiting

Squamous Cell Carcinoma of Head and Neck

NCT07369882 2026-01-27

Comparison of Efficacy Between De-escalated Surgery and Standard Surgery After Neoadjuvant Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase NA Recruiting

Squamous Cell Carcinoma of Head and Neck

NCT01154920 2025-12-17

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01720563 2025-06-04

A Phase II Trial of PG2 in Patients With Advanced Pharyngeal or Laryngeal Squamous Cell Carcinoma Under Concurrent Chemoradiotherapy

Phase 2 Terminated

Squamous Cell Carcinoma of Head and Neck

NCT03107182 2025-05-06

OPTIMA-II

Phase 2 Completed

72 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck

NCT03721757 2025-02-25

NICO

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT05217212 2023-10-10

Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer?

Squamous Cell Carcinoma of Head and Neck

NCT05993858 2023-08-15

PC-1

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck

NCT05980715 2023-08-08

HNC-SYSU-003

Phase 3 Recruiting

Squamous Cell Carcinoma of Head and Neck

NCT02207439 2023-07-25

Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

Phase 2 Completed

18 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck

NCT02952586 2021-09-22

Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)

Phase 3 Terminated

697 enrolled 26 charts

Squamous Cell Carcinoma of Head and Neck

NCT04296747 2020-03-05

Toripalimab in Combination With Chemotherapy as Induced Chemotherapy for Localized Hypopharyngeal Cancer

Phase 2 Unknown

Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Neoplasms

NCT03424291 2018-02-06

A Retrospective Clinical Study of Apatinib in Combination With Radiotherapy / Chemotherapy Second-line and Above in the Treatment of Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma

Phase 2 Unknown

Squamous Cell Carcinoma of Head and Neck

NCT02352792 2015-02-02

Hypoxia-based Dose Escalation With Radiochemotherapy in Head and Neck Cancer

Phase NA Unknown

Squamous Cell Carcinoma of Head and Neck

NCT01301248 2011-05-17

Cisplatin Chemoradiation With or Without Cetuximab for Locoregionally Advanced Squamous Cell Carcinomas (SCC) of the Head and Neck

Phase 2 Unknown

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms