Clinical Trials

Squamous Cell Carcinoma of Head and Neck

NCT05526924 2026-03-04

Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer

Phase 1 Recruiting

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07026474 2026-03-02

RePaIr-HN

Phase 3 Recruiting

214 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06557889 2026-02-11

REDUCE

Phase 2 Recruiting

86 enrolled

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck

NCT01154920 2025-12-17

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

128 enrolled

Phase 3 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03340896 2025-09-02

SALTORL

256 enrolled

Squamous Cell Carcinoma of Head and Neck, Laryngeal Diseases

NCT05446467 2025-08-20

Pembrolizumab in Combination With Low-dose PFas Neoadjuvant Treatment for Locally Advanced HNSCC

Phase 2 Recruiting

80 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00665392 2025-08-01

ECHO-07

42 enrolled 24 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT03944915 2025-05-11

DEPEND

35 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT03107182 2025-05-06

OPTIMA-II

72 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck

NCT00544414 2025-02-19

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

31 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04649476 2025-01-10

NEOPBOSCC

68 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck

NCT02258659 2024-09-24

OPTIMA

62 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT01847326 2024-07-31

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

Phase 1 Completed

48 enrolled

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT02778191 2024-05-06

Comparison of Concomitant Cisplatin Versus Carboplatin and 5-fluorouracil With Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma

Completed

413 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05125055 2023-11-22

Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC

Phase 2/3 Recruiting

80 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06102395 2023-10-30

Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC

Phase 3 Recruiting

272 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06081582 2023-10-13

Toripalimab in Combined With Cetuximab，Chemotherapy for Conversion Therapy of Locally Nonresectable OCSCC

Phase 2 Unknown

33 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05862168 2023-07-17

Neoadjuvant Treatment of Tislelizumab Combined Chemotherapy for Locally Advanced Oral Squamous Cell Carcinoma ：A Single-arm, Prospective, Phase II Trial

Phase 2 Recruiting

30 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT02268695 2022-08-23

TPExtreme

541 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT01864772 2022-08-19

ELANFIT

85 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT01884259 2022-05-26

HNO-2

100 enrolled

Squamous Cell Carcinoma of Head and Neck, Laryngeal Diseases

NCT00003627 2021-02-21

Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Advanced Cancer of the Oropharynx or Hypopharynx

160 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00006051 2021-02-21

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00736944 2020-09-09

Trial of 2 Cycles of Induction Chemo With Abraxane, Cetuximab, Cisplatin, & 5-FU for Advanced Head and Neck Cancer

30 enrolled 26 charts

Squamous Cell Carcinoma of Head and Neck

NCT00608205 2020-08-06

Radiation Therapy Cisplatin With or Without Fluorouracil Patients With Stage III or Stage IV Head and Neck Cancer

69 enrolled 47 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00721513 2020-04-07

Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

20 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04164238 2019-11-15

Neoadjuvant Anti-PD-1 Antibody (Toripalimab) or Combined With Chemotherapy in HNSCC Patients

Phase 2 Unknown

90 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT01233843 2019-01-18

2007/02

370 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00352118 2017-12-28

Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

Phase 2 Terminated

4 enrolled 4 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Xerostomia, Mucositis

NCT01221753 2017-12-06

Docetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma Study

Phase 2 Terminated

7 enrolled 6 charts

Squamous Cell Carcinoma of Head and Neck

NCT00400205 2017-11-06

Study of Induction Docetaxel, Cisplatin and 5-Fluorouracil

Phase 2 Terminated

14 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Mouth Neoplasms

NCT00513383 2017-03-01

Panitumumab Chemoradiotherapy Chemotherapy for Squamous Cancer of the Head and Neck

Phase 1 Completed

34 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Adenosquamous

NCT00003582 2016-12-15

Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer

36 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Unknown Primary

NCT01108042 2016-05-18

TPF-Induction Chemotherapy of Oropharyngeal and Cavity of the Mouth Cancer

71 enrolled

Squamous Cell Carcinoma of Head and Neck, Oropharyngeal Neoplasms

NCT02047201 2016-03-02

Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00508664 2015-06-02

DeLOS II

180 enrolled

Squamous Cell Carcinoma of Head and Neck, Laryngeal Neoplasms

NCT01425736 2014-06-03

Nimotuzumab in Combination With TPF(Cisplatin ,Fluorouracil and Docetaxel) for Head and Neck Squamous Cell Carcinoma

91 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00095875 2013-11-19

Combination Chemotherapy and Radiation in Treating Patients With Stage III or IV Head and Neck Cancer (Paradigm Trial)

145 enrolled 10 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00352105 2012-11-05

Cisplatin, Fluorouracil, Iressa, and Radiation Therapy Patients With Locally Advanced Head and Neck Cancer

60 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00910117 2012-02-20

Induction Chemotherapy With Nimotuzumab in Locally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00158652 2011-11-08

Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC

840 enrolled

Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00402545 2009-11-02

C-TPF in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Phase 1 Completed

29 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00139269 2008-06-04

Study of Docetaxel in Combination With Cisplatin and 5-Fluorouracil in Locally Advanced Squamous Cell Carcinoma of the Head and Neck

38 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00139230 2008-06-03

Combination Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT00162708 2005-09-13

Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC

Phase 2/3 Completed

120 enrolled