Clinical Trials Browser

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05544136 2026-02-27

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

Phase 2 Recruiting

12 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06957938 2025-05-08

Comparing Neoadjuvant Chemotherapy Combined With PD-1 Inhibitor Versus Neoadjuvant Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Carcinoma

Phase 3 Not yet recruiting

168 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms

NCT00544414 2025-02-19

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

Phase 2 Completed

31 enrolled 8 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT05724329 2024-09-19

Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01)

Phase 2 Active not recruiting

24 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05582265 2024-05-17

Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma (REDUCTION-I)

Phase 3 Recruiting

537 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04929067 2023-02-17

Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma: a Phase II Clinical Trial

Phase 2 Unknown

39 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05476965 2022-07-27

iCSDeR

Phase 2 Unknown

20 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04849377 2022-07-07

RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC

Phase 2 Withdrawn

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05351762 2022-07-05

Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCC

Phase 2 Unknown

55 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03923998 2019-04-23

Adjuvant ChemoRadiotherapy Prior to Surgery in Stage IVa Oral Cancers

Phase EARLY_PHASE1 Completed

8 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms

NCT00002839 2018-07-09

Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx

Phase 3 Completed

564 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00498953 2018-07-09

Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx

Phase 1/2 Completed

7 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00601913 2018-07-05

Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery

Phase EARLY_PHASE1 Completed

24 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00751816 2015-12-10

Head & Neck Cancer Survivorship: Physical and Functional Status

Completed

23 enrolled

CNSHead & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00002702 2013-08-26

Surgery and Radiation Therapy With or Without Interleukin-2 in Treating Patients With Cancer of the Mouth or Oropharynx

Phase 3 Unknown

260 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT00276523 2012-10-31

PEG-interferon Alfa-2b in Treating Patients With Stage II, Stage III, or Stage IV Head and Neck Cancer That Can Be Removed By Surgery

Phase 2 Completed

3 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00357617 2010-12-24

Celecoxib in Treating Patients With Head and Neck Cancer That Can Be Removed By Surgery

Phase 1/2 Unknown

24 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

Clinical Trials

Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

Comparing Neoadjuvant Chemotherapy Combined With PD-1 Inhibitor Versus Neoadjuvant Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Carcinoma

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01)

Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma (REDUCTION-I)

Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma: a Phase II Clinical Trial

iCSDeR

RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC

Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCC

Adjuvant ChemoRadiotherapy Prior to Surgery in Stage IVa Oral Cancers

Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx

Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx

Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery

Head & Neck Cancer Survivorship: Physical and Functional Status

Surgery and Radiation Therapy With or Without Interleukin-2 in Treating Patients With Cancer of the Mouth or Oropharynx

PEG-interferon Alfa-2b in Treating Patients With Stage II, Stage III, or Stage IV Head and Neck Cancer That Can Be Removed By Surgery

Celecoxib in Treating Patients With Head and Neck Cancer That Can Be Removed By Surgery