Clinical Trials

53 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT07121595 2025-08-13

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

50 enrolled

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms

NCT07090707 2025-07-29

PD-1 Inhibitor Therapy Versus Radiotherapy in MPR Patients With Locally Advanced HNSCC After Neoadjuvant Immunochemotherapy (HNC-SYSU-006)

50 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT07055841 2025-07-09

Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

69 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06494995 2025-06-04

AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy

52 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Squamous Cell Carcinoma of Head and Neck

NCT06673693 2025-04-16

NEOSTART

24 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05608369 2025-04-04

HPV

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT03721757 2025-02-25

NICO

21 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT00544414 2025-02-19

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

31 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00559156 2025-02-13

Arginine/Omega-3 Fatty Acids/Nucleotides Nutritional Supplement in Treating Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

46 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT03715946 2025-01-13

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

40 enrolled 69 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

NCT06725498 2024-12-10

Intra-arterial Chemotherapy Combined with Radiotherapy and Immunotherapy for HNSCC

50 enrolled

Phase 2 Active not recruiting

Squamous Cell Carcinoma of Head and Neck

NCT04452032 2024-11-08

StomRay

40 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT02258659 2024-09-24

OPTIMA

62 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT00720304 2024-08-22

Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and Neck

43 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT06170697 2023-12-20

Advanced First-line Treatment of Short-term Postoperative Progression of Head and Neck Squamous Cell Carcinoma

46 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT03624231 2023-08-31

DURTRE-RAD

18 enrolled

Phase 2 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck

NCT05993858 2023-08-15

PC-1

33 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00096174 2023-06-29

Phase II Study of Concurrent C225, Cisplatin and Radiation in Stage IV Squamous Cell Carcinoma of the Head and Neck

69 enrolled 7 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00014118 2023-06-15

Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01590355 2023-03-08

ORATOR

68 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05749042 2023-03-01

A Study of Concurrent Chemoradiotherapy Based of Cisplatin With or Without Sintilimab as First-line Therapy for Patients With Advanced Oral Cavity Squamous Cell Carcinoma

70 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT02707588 2023-02-28

PembroRad

133 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05343325 2022-12-29

The Efficacy and Safety of Neoadjuvant Low-dose Radiotherapy Combined With Chemoimmunotherapy in Locally Advanced HNSCC

25 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05476965 2022-07-27

iCSDeR

20 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04849377 2022-07-07

RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck

NCT03330249 2022-03-11

CisFRad

124 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00566540 2021-11-26

Ph 2 Intensification Regimen for Previously Untreated, Resectable, Advanced Squamous Cell Cancer

Phase 2 Terminated

11 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04607642 2021-10-11

Trial of BMX-001 or Placebo in Head and Neck Cancer Patients

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00006051 2021-02-21

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00005088 2020-10-22

Radiation Therapy and Cisplatin in Treating Patients With Advanced Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00084318 2018-12-12

Adjuvant Cetuximab and Chemoradiotherapy Using Either Cisplatin or Docetaxel in Treating Patients With Resected Stage III or Stage IV Squamous Cell Carcinoma or Lymphoepithelioma of the Head and Neck

238 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00352118 2017-12-28

Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

Phase 2 Terminated

4 enrolled 4 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Xerostomia, Mucositis

NCT00895245 2017-05-18

Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

Phase 2 Terminated

6 enrolled 5 charts

Squamous Cell Carcinoma of Head and Neck, Nausea, Vomiting

NCT00005087 2015-11-17

Paclitaxel, Cisplatin, and Filgrastim Combined With Radiation Therapy in Treating Patients With Locally Recurrent Head and Neck Cancer

105 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00011999 2015-11-17

Chemotherapy and Radiation Therapy Following Surgery in Treating Patients With Head and Neck Cancer

70 enrolled