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Phase

Phase 2 3Phase 1/2 2

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2Gynecologic 1Breast 1

Conditions

Breast Neoplasms 16Brain Neoplasms 4Ovarian Neoplasms 3Neoplasm Metastasis 3Endometrial Neoplasms 3Squamous Cell Carcinoma of Head and Neck 2Neoplasms by Site 2Neoplasms 2Glioma 2Glioblastoma 2Colorectal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Breast Diseases 2Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Solid Tumor, Adult 1Sarcoma, Kaposi 1Sarcoma, Ewing 1Sarcoma 1Rhabdomyosarcoma 1Rhabdoid Tumor 1Rectal Neoplasms 1Prostatic Neoplasms 1Osteosarcoma 1Neurofibromatosis 1 1Neuroblastoma 1Multiple Myeloma 1Medulloblastoma 1Lung Neoplasms 1Liposarcoma 1

Interventions

pembrolizumab 47Cisplatin 24Cetuximab 23Paclitaxel 18Nivolumab 18Radiotherapy 15Docetaxel 15Carboplatin 14Fluorouracil 11tremelimumab 7durvalumab 7Erlotinib Hydrochloride 6avelumab 5Radiotherapy, Intensity-Modulated 5Radiosurgery 5Pemetrexed 4Ipilimumab 4Immunoglobulin G 4Gemcitabine 4Fulvestrant 4Capecitabine 4Bevacizumab 4epacadostat 3cemiplimab 3atezolizumab 3Taxes 3Radiation 3Everolimus 3Cyclophosphamide 3Amifostine 3

Date Range

30 days90 days1 yearAll

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Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × Squamous Cell Carcinoma of Head and Neck × abemaciclib × Clear all
NCT05768139 2026-06-04

PIKALO-1

Eli Lilly and Company

Phase 1/2 Recruiting
880 enrolled
BreastGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Breast Diseases, Breast Neoplasms, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Neoplasms, Neoplasms by Site, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Endometrial Neoplasms

NCT03655444 2020-12-03

Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy

Washington University School of Medicine

Phase 1/2 Terminated
6 enrolled 12 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

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