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Phase

Phase 2 3Phase 1/2 1

Status

Terminated 2Unknown 1Completed 1

Sponsor Class

OTHER 4INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Head & Neck 4

Conditions

Breast Neoplasms 47Neoplasm Metastasis 9Neoplasms 8Prostatic Neoplasms 7Brain Neoplasms 7Endometrial Neoplasms 6Glioblastoma 5Triple Negative Breast Neoplasms 4Squamous Cell Carcinoma of Head and Neck 4Ovarian Neoplasms 4Head and Neck Neoplasms 4Meningioma 3Carcinoma, Renal Cell 3Sarcoma 2Recurrence 2Pancreatic Neoplasms 2Osteosarcoma 2Oligodendroglioma 2Multiple Myeloma 2Lymphoma, Non-Hodgkin 2Liposarcoma 2Hematologic Neoplasms 2Glioma 2Breast Neoplasms, Male 2Breast Diseases 2Breast Cancer Female 2Venous Thromboembolism 1Urologic Neoplasms 1Urinary Bladder Neoplasms 1Unilateral Breast Neoplasms 1

Interventions

Cisplatin 168Radiotherapy 110pembrolizumab 96Cetuximab 95Docetaxel 74Carboplatin 74Radiotherapy, Intensity-Modulated 55Paclitaxel 51Nivolumab 50Fluorouracil 47Surgical Procedures, Operative 28Radiation 26Magnetic Resonance Spectroscopy 25durvalumab 23Drug Therapy 23Radiosurgery 21Biopsy 19Albumin-Bound Paclitaxel 19130-nm albumin-bound paclitaxel 18Taxes 17tislelizumab 16toripalimab 15Chemoradiotherapy 15Neoadjuvant Therapy 14Erlotinib Hydrochloride 14Blood Specimen Collection 14camrelizumab 13Immunohistochemistry 13Specimen Handling 12tremelimumab 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × Squamous Cell Carcinoma of Head and Neck × abemaciclib × Clear all
NCT04169074 2026-05-22

Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)

University of Arizona

Phase 2 Terminated
7 enrolled 14 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT03292250 2022-03-29

Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)]

Seoul National University Hospital

Phase 2 Completed
180 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03655444 2020-12-03

Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy

Washington University School of Medicine

Phase 1/2 Terminated
6 enrolled 12 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03356587 2017-11-29

A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy

Seoul National University Hospital

Phase 2 Unknown
32 enrolled
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

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