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Phase

Phase 2 1Phase 1/2 1

Status

Terminated 2Unknown 1Recruiting 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Head & Neck 2

Conditions

Breast Neoplasms 10Prostatic Neoplasms 3Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Neoplasms 2Neoplasm Metastasis 2Triple Negative Breast Neoplasms 1Thrombocytosis 1Sarcoma 1Primary Myelofibrosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Neoplasms, Squamous Cell 1Myeloproliferative Disorders 1Myelodysplastic-Myeloproliferative Diseases 1Myelodysplastic Syndromes 1Multiple Myeloma 1Lymphoma, Non-Hodgkin 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Chronic-Phase 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia, Myeloid, Acute 1Leukemia, Myeloid, Accelerated Phase 1Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1Leukemia, Lymphocytic, Chronic, B-Cell 1Hodgkin Disease 1Hematologic Neoplasms 1Head and Neck Neoplasms 1Glioblastoma 1Fibrocystic Breast Disease 1

Interventions

pembrolizumab 40Cisplatin 32Radiotherapy 22Cetuximab 22Radiotherapy, Intensity-Modulated 15Docetaxel 12Nivolumab 11Paclitaxel 10Fluorouracil 10Carboplatin 8Radiosurgery 6epacadostat 5Radiation 5spartalizumab 4avelumab 4Surgical Procedures, Operative 4Radiotherapy, Conformal 4Immunoglobulin G 4Biopsy 4ribociclib 3durvalumab 3bempegaldesleukin 3Magnetic Resonance Spectroscopy 3Ipilimumab 3Everolimus 3Erlotinib Hydrochloride 3Disulfides 3Cyclophosphamide 3Albumin-Bound Paclitaxel 3utomilumab 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Terminated × Squamous Cell Carcinoma of Head and Neck × abemaciclib × Clear all
NCT04169074 2026-05-22

Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)

University of Arizona

Phase 2 Terminated
7 enrolled 14 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT03655444 2020-12-03

Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy

Washington University School of Medicine

Phase 1/2 Terminated
6 enrolled 12 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck

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