Clinical Trials

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Salivary Gland Neoplasms

NCT06645808 2025-12-29

VARTUTRACE

BreastCNSGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

32 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Stomach Neoplasms

NCT05183048 2025-12-26

Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma

14 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05845307 2025-12-08

Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma of Head and Neck

NCT06914999 2025-10-22

Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer

20 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Oropharyngeal Neoplasms

NCT07168785 2025-09-11

[18F]-AraG PET Imaging in LA HNSCC

5 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06273852 2025-08-11

A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors

8 enrolled

BreastHead & Neck

Squamous Cell Carcinoma of Head and Neck, Triple Negative Breast Neoplasms

NCT06700070 2025-08-11

A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors

12 enrolled

BreastHead & Neck

Squamous Cell Carcinoma of Head and Neck, Triple Negative Breast Neoplasms

NCT06086925 2025-07-11

A Window of Opportunity Study of Black Raspberry for Patients With HNSCC

Phase EARLY_PHASE1 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck

NCT07028918 2025-06-19

NCLDR

35 enrolled

Acidemia, isovaleric, Squamous Cell Carcinoma of Head and Neck

NCT03618654 2025-05-15

Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

38 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05322135 2025-04-09

A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell Carcinoma

3 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02827838 2025-03-17

Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer

17 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT04883645 2025-01-28

Neoadjuvant Imiquimod Immunotherapy for Oral Cancer

16 enrolled 10 charts

Squamous Cell Carcinoma of Head and Neck

NCT06366451 2025-01-20

PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC

15 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03459729 2025-01-16

Pharmacokinetic (PK) Analysis of Antitumor B in Patients With Oral Cancer

6 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck

NCT05996432 2024-09-23

Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy

48 enrolled

CNSHead & Neck

Squamous Cell Carcinoma of Head and Neck, Brain Neoplasms

NCT06413095 2024-05-14

PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS

13 enrolled

Head & NeckSarcoma

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Sarcoma

NCT03868020 2024-03-28

Fluciclovine F18 PET/CT in Identifying the Origin of Head and Neck Squamous Cell Carcinoma in Patients With Metastatic Cervical Nodal Disease

16 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06062602 2023-10-06

PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC

15 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03575598 2023-07-27

SNOW

10 enrolled

Phase EARLY_PHASE1 Unknown

Squamous Cell Carcinoma of Head and Neck

NCT05831930 2023-04-26

The Effect of Nitozumab in the Treatment of Head and Neck Squamous Cell Carcinoma

62 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT02582008 2023-03-22

Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

9 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma

NCT04065555 2022-07-29

Intratumoral Microdosing of TAK-981 in Head and Neck Cancer

12 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04891718 2022-07-08

CIVO Intratumoural Microdosing of Anti-Cancer Therapies in Australia

DermatologicHead & NeckLymphoidSarcoma

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Lymphoma, Melanoma, Sarcoma

NCT04272333 2022-04-14

Intratumoral Microdosing of Motolimod in HNSCC

1 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01895829 2021-09-21

Ferumoxytol - Iron Oxide Nanoparticle Magnetic Resonance Dynamic Contrast Enhanced MRI

7 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01967927 2021-08-19

Understanding GRID Radiation Therapy Effects on Human Tumor Oxygenation and Interstitial Pressure to Increase Translation of Solid Tumor Therapy

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Neoplasms

NCT03182959 2021-06-21

Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer

6 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma in Situ, Head and Neck Neoplasms, Hyperplasia

NCT02794675 2020-12-23

Intraoperative Placement of Cesium-131 Permanent Interstitial Brachytherapy in Head and Neck Cancer

15 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT03923998 2019-04-23

Adjuvant ChemoRadiotherapy Prior to Surgery in Stage IVa Oral Cancers

8 enrolled

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms

NCT03179956 2019-02-25

Impact of Ribociclib on Head and Neck Squamous Cell Cancer

1 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00499733 2019-01-18

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcomaThoracic

19 enrolled

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Osteosarcoma, Tongue Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Intraocular Lymphoma

NCT00601913 2018-07-05

Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery

24 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02608736 2018-02-01

GAMA

42 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT00757549 2017-10-31

3'-Deoxy-3'-[18F] Fluorothymidine and Fludeoxyglucose F 18 PET Scans in Evaluating Response to Cetuximab, Cisplatin, and Radiation Therapy in Patients With Advanced Cancer of the Oropharynx, Larynx, or Hypopharynx

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02593929 2017-06-08

Pharmacodynamic Effects and Predictive Biomarkers With Ruxolitinib in Operable Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms

NCT02402348 2017-02-08

Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

3 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01275183 2015-06-18

Pilot Study of Raltegravir and Cisplatin in Squamous Cell Carcinoma of Head and Neck

5 enrolled

Phase EARLY_PHASE1 Unknown

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT00536952 2013-06-27

Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy

36 enrolled