Announcements Trials
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Phase

Phase 3 2Phase 2 2Phase NA 1

Status

Completed 5

Sponsor Class

NETWORK 7INDUSTRY 5OTHER 3

Study Type

Interventional 5

Sponsor

Cancer Type

Gynecologic 5Gastrointestinal 1

Conditions

Neoplasms 805Carcinoma, Non-Small-Cell Lung 766Breast Neoplasms 731Neoplasm Metastasis 340Colorectal Neoplasms 339Prostatic Neoplasms 324Multiple Myeloma 309Melanoma 305Recurrence 237Ovarian Neoplasms 236Leukemia, Myeloid, Acute 236Lymphoma, Non-Hodgkin 213Lung Neoplasms 211Carcinoma, Renal Cell 200Lymphoma 189Lymphoma, Follicular 163Pancreatic Neoplasms 157Leukemia, Lymphocytic, Chronic, B-Cell 149Carcinoma, Hepatocellular 140Stomach Neoplasms 137Leukemia 133Head and Neck Neoplasms 128Lymphoma, Large B-Cell, Diffuse 126Parkinson Disease 4, Autosomal Dominant Lewy Body 119Squamous Cell Carcinoma of Head and Neck 110Urinary Bladder Neoplasms 109Carcinoma 101Small Cell Lung Carcinoma 99Triple Negative Breast Neoplasms 97Glioblastoma 96

Interventions

VGX-3100 3Radiofrequency Ablation 1Electroporation 14,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × Has results × Squamous Intraepithelial Lesions × Clear all
NCT03721978 2024-10-17

REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

Inovio Pharmaceuticals

Phase 3 Completed
203 enrolled 34 charts
Gynecologic

Squamous Intraepithelial Lesions, Uterine Cervical Dysplasia

NCT03185013 2023-07-27

REVEAL 1

Inovio Pharmaceuticals

Phase 3 Completed
201 enrolled 23 charts
Gynecologic

Squamous Intraepithelial Lesions, Uterine Cervical Dysplasia

NCT03499795 2023-07-14

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Inovio Pharmaceuticals

Phase 2 Completed
23 enrolled 19 charts
GastrointestinalGynecologic

Squamous Intraepithelial Lesions, Anus Neoplasms

NCT02189161 2016-07-14

A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia

Medtronic - MITG

Phase NA Completed
10 enrolled 6 charts
Gynecologic

Squamous Intraepithelial Lesions

NCT00285207 2010-10-11

Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix

Tigris Pharmaceuticals

Phase 2 Completed
147 enrolled 6 charts
Gynecologic

Squamous Intraepithelial Lesions, Uterine Cervical Dysplasia

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