Clinical Trials Browser

OTHER × Stomach Neoplasms × Irinotecan × Clear all

NCT02366819 2026-03-30

Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer

Phase 4 Suspended

Gastrointestinal

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT07309185 2025-12-30

Adebrelimab Combined With Famitinib and Irinotecan in Advanced Gastric Cancer After Failure of First-Line Therapy

Phase 2 Recruiting

Gastrointestinal

Stomach Neoplasms

NCT04329494 2025-12-10

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Phase 1 Recruiting

GastrointestinalGynecologic

Appendiceal Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT05379790 2025-04-01

Concomitant Intraperitoneal and Systemic Chemotherapy in Patients With Extensive Peritoneal Carcinomatosis of Gastric Origin

Phase 1 Completed

Gastrointestinal

Stomach Neoplasms

NCT02485834 2025-01-20

FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer

Phase 2 Terminated

5 enrolled 11 charts

Gastrointestinal

Stomach Neoplasms

NCT03368963 2025-01-07

TAS102 in Combination With NAL-IRI in Advanced GI Cancers

Phase 1/2 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT04770623 2024-01-30

Docetaxel and Irinotecan in Gastric Cancer

Phase 2 Completed

Gastrointestinal

Stomach Neoplasms

NCT06196554 2024-01-09

Gastric Cancer Organoids in the Screening of Neoadjuvant Drugs

Gastrointestinal

Stomach Neoplasms

NCT02333188 2023-05-31

Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer

Phase 1 Completed

Gastrointestinal

Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Cholangiocarcinoma

NCT05025033 2023-01-18

Chemotherapy Combined With Apatinib and PD-1 Antibody

Phase 2 Completed

Gastrointestinal

Stomach Neoplasms

NCT05643677 2022-12-09

Fruquintinib Plus Irinotecan in the Treatment of Advanced Gastric Cancer

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT00911820 2022-11-08

Cisplatin, Irinotecan and Bevacizumab (PCA) Versus Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer

Phase 2 Completed

88 enrolled 14 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT04358354 2021-07-19

Triplet Combination of Cytotoxics as First-line Treatment for Metastatic Gastric Cancer

Phase 3 Unknown

Gastrointestinal

Stomach Neoplasms

NCT04934618 2021-06-22

A Phase II Study of Carelizumab Combined With Irinotecan and Apatinib of Second-line Treatment for Advanced Gastric Cancer

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT04915807 2021-06-07

Real-world Data (RWD) of Ramucirumab Plus Paclitaxel

Gastrointestinal

Stomach Neoplasms

NCT04393584 2021-04-13

RusGCG-01

Phase 2/3 Unknown

Gastrointestinal

Gastrointestinal Neoplasms, Stomach Neoplasms

NCT04442984 2021-04-13

IRIGA

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT00952003 2020-11-30

Oxaliplatin/Irinotecan/Bevacizumab Followed by Docetaxel/Bevacizumab in Inoperable Locally Advanced or Metastatic Gastric Cancer Patients

Phase 2 Completed

Gastrointestinal

Stomach Neoplasms

NCT01928290 2020-08-25

FOLFIRINOX

Phase 2 Completed

67 enrolled 14 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT04358341 2020-08-24

Pegliposomal Doxorubicin and 5-fluorouracil as Second Line Therapy for Metastatic Gastric Cancer

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT00003748 2020-08-03

Irinotecan in Treating Patients With Esophageal or Stomach Cancer

Phase 2 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT00020761 2020-08-03

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach

Phase 2 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT01643499 2020-05-08

Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies

Phase 1 Completed

Gastrointestinal

Bile Duct Neoplasms, Colonic Neoplasms, Gallbladder Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT01271582 2019-01-29

Investigation of Association Between UGT1A1 Polymorphisms and Irinotecan Toxicity in Korean Patients

Phase 4 Unknown

Gastrointestinal

Neutropenia, Stomach Neoplasms, Colorectal Neoplasms

NCT03668418 2018-09-12

xenoZ

Gastrointestinal

Biliary Tract Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT00003867 2018-09-10

Irinotecan and Capecitabine in Treating Patients With Solid Tumors

Phase 1 Completed

BreastGastrointestinal

Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT02358863 2018-09-06

mEGA

Phase NA Terminated

13 enrolled 6 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT00183872 2018-02-19

Study of Irinotecan and Docetaxel in Patients With Metastatic or Unresectable Gastric or Gastroesophageal Junction Adenocarcinoma

Phase 2 Completed

40 enrolled 10 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT03400592 2018-01-17

NIEGA

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT00848783 2018-01-08

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Phase 2 Terminated

8 enrolled 9 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT00201747 2017-12-06

Sequentially Administered CPT-11 and Mitomycin C in Patients With Advanced Esophageal and Stomach Cancer

Phase 2 Completed

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT03061058 2017-09-15

Individualized Intraperitoneal and System Chemotherapy Versus System Chemotherapy as First-line Chemotherapy for AGC

Phase 3 Unknown

Gastrointestinal

Stomach Neoplasms

NCT02527785 2017-08-23

Study of Oxaliplatin, Irinotecan, and S-1 in Gastric Cancer

Phase 2 Completed

Gastrointestinal

Stomach Neoplasms

NCT00394433 2017-08-01

Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer

Phase 2 Completed

38 enrolled 10 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT00654160 2017-05-25

Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer

Phase 1 Completed

GastrointestinalSarcoma

Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Gastrointestinal Stromal Tumors

NCT00003137 2016-07-14

Irinotecan in Treating Patients With Advanced Cancer of the Stomach

Phase 2 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT00004235 2016-07-14

Docetaxel and Irinotecan in Treating Patients With Advanced Cancer of the Esophagus or Stomach

Phase 2 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT00524186 2016-06-21

Sunitinib, Irinotecan, Fluorouracil, and Leucovorin In Treating Patients With Advanced Stomach Cancer or Gastroesophageal Cancer

Phase 1 Terminated

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT00737438 2016-02-03

Pre-operative Chemotherapy Plus Bevacizumab With Early Salvage Therapy Based on PET Assessment of Response in Patients With Locally Advanced But Resectable Gastric and GEJ Adenocarcinoma

Phase 2 Completed

22 enrolled 6 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT02662959 2016-01-26

Irinotecan as 3rd Line Therapy in Gastric Cancer

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT02283359 2016-01-15

Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus

Phase 1 Terminated

Gastrointestinal

Adenocarcinoma, Carcinoma, Esophageal Neoplasms, Neoplasm Metastasis, Recurrence, Stomach Neoplasms

NCT00857246 2015-12-07

Pre-operation Chemo and Antibody Therapy Followed by Surgical Resection and Adjuvant Chemoradiation for Gastric Cancer

Phase 2 Completed

30 enrolled 11 charts

Gastrointestinal

Stomach Neoplasms

NCT00397904 2015-11-25

Cetuximab, Cisplatin, and Irinotecan in Treating Patients With Metastatic Esophageal Cancer, Gastroesophageal Junction Cancer, or Gastric Cancer That Did Not Respond to Previous Irinotecan and Cisplatin

Phase 2 Completed

16 enrolled 6 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT02401971 2015-03-30

ITAGC

Phase 4 Unknown

Gastrointestinal

Stomach Neoplasms

NCT01138904 2014-11-04

FOLFOX Followed by FOLFIRI or Reverse Sequence Treatment in Advanced Gastric Cancer (AGC)

Phase 2 Completed

Gastrointestinal

Stomach Neoplasms

NCT00183846 2014-05-22

Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Cancers

Phase 1 Completed

Gastrointestinal

Bile Duct Neoplasms, Duodenal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT00183859 2014-05-22

Clinical and Pharmacokinetic Trial of Intra-Abdominal Irinotecan

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Stomach Neoplasms

NCT01964027 2013-10-17

SIEG

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT00166881 2013-07-08

P-HDFL-DI

Phase 2 Completed

Gastrointestinal

Stomach Neoplasms

NCT00537121 2013-06-28

Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal Cancer

Phase 1 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Stomach Neoplasms