Clinical Trials Browser

Gastro-enteropancreatic neuroendocrine tumor, Anus Neoplasms, Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Adenoma, Islet Cell, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT05898854 2025-12-30

[68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer

Phase 2 Completed

20 enrolled

Gastrointestinal

Neoplasms, Stomach Neoplasms

NCT05419362 2025-12-16

GEN-001 in Combination With Avelumab for Patients With PD-L1 Positive Gastric Cancer

Phase 2 Completed

42 enrolled

Gastrointestinal

Stomach Neoplasms

NCT04798781 2025-12-11

Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma

Phase 2 Completed

16 enrolled 13 charts

Gastrointestinal

Carcinoma, Hepatocellular, Stomach Neoplasms

NCT03797326 2025-11-17

LEAP-005

Phase 2 Completed

611 enrolled 27 charts

BreastCNSGastrointestinalGynecologic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Biliary Tract Neoplasms, Glioblastoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01191697 2025-11-03

CAPOX, Bevacizumab and Trastuzumab for Patients With HER2-Positive Metastatic Esophagogastric Cancer

Phase 2 Completed

37 enrolled 11 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT03620643 2025-10-30

ROLo

Phase 2 Completed

33 enrolled 13 charts

BreastGastrointestinal

Stomach Neoplasms, Carcinoma, Lobular, Triple Negative Breast Neoplasms

NCT04768686 2025-09-25

FLX475 Combined With Pembrolizumab in Patients With Advanced or Metastatic Gastric Cancer

Phase 2 Completed

20 enrolled 14 charts

Gastrointestinal

Stomach Neoplasms

NCT05104567 2025-09-24

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

Phase 2 Completed

138 enrolled 32 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Carcinoma, Hepatocellular, Stomach Neoplasms, Colorectal Neoplasms

NCT03929666 2025-09-12

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

Phase 2 Completed

74 enrolled

Gastrointestinal

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05007106 2025-08-14

KEYVIBE-005

Phase 2 Completed

613 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT02205047 2025-07-31

INNOVATION

Phase 2 Completed

172 enrolled

Gastrointestinal

Stomach Neoplasms

NCT03636893 2025-07-23

Dragon III: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer

Phase 2 Completed

74 enrolled 12 charts

Gastrointestinal

Stomach Neoplasms

NCT02078700 2025-06-25

Feasibility of an Early Palliative Care Intervention for Metastatic Cancer Patients. A Phase 2 Study.

Phase 2 Completed

40 enrolled

GastrointestinalOther solid neoplasmThoracic

Lung Neoplasms, Mesothelioma, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT06812403 2025-06-25

Combination COMBO Endoscopy Oropharyngeal Airway With High-Flow Nasal Cannula Oxygenation in Sedated Gastrointestinal Endoscopy for Obese Patients

Phase 2 Completed

50 enrolled

Gastrointestinal

Hypoxia, Colonic Polyps, Esophageal Neoplasms, Stomach Neoplasms

NCT06804876 2025-05-21

COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Obese Patients

Phase 2 Completed

107 enrolled

Gastrointestinal

Hypoxia, Colonic Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT03050879 2025-04-24

ICGTinLG

Phase 2 Completed

266 enrolled

Gastrointestinal

Stomach Neoplasms

NCT03609359 2025-04-16

Lenva+Pembro

Phase 2 Completed

29 enrolled 20 charts

Gastrointestinal

Stomach Neoplasms

NCT03064490 2025-04-10

PROCEED

Phase 2 Completed

35 enrolled 8 charts

Gastrointestinal

Stomach Neoplasms

NCT03627728 2025-03-13

a-MANTRA

Phase 2 Completed

67 enrolled

Gastrointestinal

Stomach Neoplasms

NCT04510064 2025-03-12

Conversion Effects of PD-1 Antibody Camrelizumab Combined With Nab-POF Regimen Chemotherpy in Patients With Initially Unresectable Locally Advanced or Limited Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma：FDZL-GC001 Trial

Phase 2 Completed

40 enrolled

Gastrointestinal

Stomach Neoplasms

NCT03092518 2025-02-19

Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology

Phase 2 Completed

27 enrolled 13 charts

Gastrointestinal

Adenocarcinoma, Stomach Neoplasms

NCT03662659 2025-02-05

An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers

Phase 2 Completed

274 enrolled 19 charts

Gastrointestinal

Stomach Neoplasms

NCT04034251 2025-02-03

Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal Carcinomatosis

Phase 2 Completed

12 enrolled 18 charts

GastrointestinalGynecologic

Adenocarcinoma, Peritoneal Neoplasms, Stomach Neoplasms

NCT04535414 2025-01-17

Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers

Phase 2 Completed

195 enrolled 10 charts

Gastrointestinal

Disease, Stomach Neoplasms

NCT00780494 2025-01-14

Ph II of Capecitabine, Carboplatin & Bevacizumab for Gastroesophageal Junction & Gastric Carcinoma

Phase 2 Completed

35 enrolled 13 charts

GastrointestinalSarcoma

Stomach Neoplasms, Gastrointestinal Stromal Tumors

NCT01876927 2025-01-09

GastroDOC

Phase 2 Completed

106 enrolled

Gastrointestinal

Stomach Neoplasms

NCT01286766 2024-12-27

Neoadjuvant Combination Chemotherapy of DCS and DCF in Patients With Locally Advanced Gastric Adenocarcinoma

Phase 2 Completed

6 enrolled

Gastrointestinal

Stomach Neoplasms

NCT03878472 2024-12-16

Neoadjuvant Immunotherapy for Resectable Gastric Cancer

Phase 2 Completed

25 enrolled

Gastrointestinal

Stomach Neoplasms

NCT04989816 2024-11-21

DG-06

Phase 2 Completed

95 enrolled 22 charts

Gastrointestinal

Adenocarcinoma, Stomach Neoplasms

NCT04871204 2024-10-31

OTIS

Phase 2 Completed

20 enrolled

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms, Weight Loss

NCT03427814 2024-10-26

Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer

Phase 2 Completed

136 enrolled 16 charts

Gastrointestinal

Stomach Neoplasms

NCT02040142 2024-10-24

HIPEC for Peritoneal Carcinomatosis

Phase 2 Completed

51 enrolled 12 charts

GastrointestinalGynecologic

Appendiceal Neoplasms, Peritoneal Neoplasms, Pseudomyxoma Peritonei, Stomach Neoplasms, Colorectal Neoplasms

NCT03469557 2024-10-23

BGB A317 in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Carcinoma

Phase 2 Completed

30 enrolled

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Stomach Neoplasms

NCT02794428 2024-10-16

Chemoprevention of Gastric Carcinogenesis

Phase 2 Completed

91 enrolled 10 charts

Gastrointestinal

Gastritis, Atrophic, Stomach Neoplasms

NCT03921021 2024-06-25

Phase 2 Study of Telomelysin (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

Phase 2 Completed

17 enrolled 13 charts

Gastrointestinal

Stomach Neoplasms

NCT03382600 2024-06-11

KEYNOTE-659

Phase 2 Completed

100 enrolled 21 charts

Gastrointestinal

Stomach Neoplasms

NCT03321630 2024-03-27

A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

Phase 2 Completed

24 enrolled 10 charts

Gastrointestinal

Stomach Neoplasms

NCT04547153 2024-03-25

Infusional Fluorouracil and Weekly Docetaxel for Gastric Cancer With Bone Marrow Involvement and DIC

Phase 2 Completed

24 enrolled

Gastrointestinal

Disseminated Intravascular Coagulation, Stomach Neoplasms

NCT03342937 2024-03-13

KeyLargo: Pembrolizumab + Oxaliplatin + Capecitabine in Gastric Cancer

Phase 2 Completed

36 enrolled 11 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT03694522 2024-02-28

FIGHT

Phase 2 Completed

155 enrolled 19 charts

Gastrointestinal

Stomach Neoplasms

NCT02918162 2024-02-15

Perioperative Chemo and Pembrolizumab in Gastric Cancer

Phase 2 Completed

49 enrolled 10 charts

Gastrointestinal

Adenocarcinoma, Stomach Neoplasms

NCT03549494 2024-02-07

Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction

Phase 2 Completed

45 enrolled

GastrointestinalHead & Neck

Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Stomach Diseases, Stomach Neoplasms

NCT04694183 2024-02-07

The Conversion Therapy of Chemotherapy Plus Camrelizumab in Metastatic Gastric Cancer

Phase 2 Completed

37 enrolled

Gastrointestinal

Neoplasm Metastasis, Stomach Neoplasms

NCT03283761 2024-02-06

FOLFOX-A in the Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma

Phase 2 Completed

39 enrolled 17 charts

Gastrointestinal

Stomach Neoplasms

NCT04770623 2024-01-30

Docetaxel and Irinotecan in Gastric Cancer

Phase 2 Completed

32 enrolled

Gastrointestinal

Stomach Neoplasms

Clinical Trials

Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors

TRACE

TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

18F-FAPI-74 GI

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

[68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer

GEN-001 in Combination With Avelumab for Patients With PD-L1 Positive Gastric Cancer

Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma

LEAP-005

CAPOX, Bevacizumab and Trastuzumab for Patients With HER2-Positive Metastatic Esophagogastric Cancer

ROLo

FLX475 Combined With Pembrolizumab in Patients With Advanced or Metastatic Gastric Cancer

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

KEYVIBE-005

INNOVATION

Dragon III: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer

Feasibility of an Early Palliative Care Intervention for Metastatic Cancer Patients. A Phase 2 Study.

Combination COMBO Endoscopy Oropharyngeal Airway With High-Flow Nasal Cannula Oxygenation in Sedated Gastrointestinal Endoscopy for Obese Patients

COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Obese Patients

ICGTinLG

Lenva+Pembro

PROCEED

a-MANTRA

Conversion Effects of PD-1 Antibody Camrelizumab Combined With Nab-POF Regimen Chemotherpy in Patients With Initially Unresectable Locally Advanced or Limited Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma：FDZL-GC001 Trial

Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology

An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers

Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal Carcinomatosis

Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers

Ph II of Capecitabine, Carboplatin & Bevacizumab for Gastroesophageal Junction & Gastric Carcinoma

GastroDOC

Neoadjuvant Combination Chemotherapy of DCS and DCF in Patients With Locally Advanced Gastric Adenocarcinoma

Neoadjuvant Immunotherapy for Resectable Gastric Cancer

DG-06

OTIS

Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer

HIPEC for Peritoneal Carcinomatosis

BGB A317 in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Carcinoma

Chemoprevention of Gastric Carcinogenesis

Phase 2 Study of Telomelysin (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

KEYNOTE-659

A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

Infusional Fluorouracil and Weekly Docetaxel for Gastric Cancer With Bone Marrow Involvement and DIC

KeyLargo: Pembrolizumab + Oxaliplatin + Capecitabine in Gastric Cancer

FIGHT

Perioperative Chemo and Pembrolizumab in Gastric Cancer

Evaluation of Ocoxin®-Viusid® in Advanced Stomach Cancer and Gastric Esophagogastric Junction

The Conversion Therapy of Chemotherapy Plus Camrelizumab in Metastatic Gastric Cancer

FOLFOX-A in the Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma

Docetaxel and Irinotecan in Gastric Cancer