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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Genitourinary 1

Conditions

Myelodysplastic Syndromes 3Small Cell Lung Carcinoma 2Melanoma 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myeloid, Acute 2Colorectal Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Urinary Bladder Neoplasms 1Urethral Neoplasms 1Ureteral Neoplasms 1Testicular Neoplasms 1Testicular Germ Cell Tumor 1Rectal Diseases 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Neoplasms, Germ Cell and Embryonal 1Neoplasms by Site 1Neoplasms 1Neoplasm Metastasis 1Myeloproliferative Disorders 1Lung Neoplasms 1Kidney Neoplasms 1Intestinal Neoplasms 1Intestinal Diseases 1Gastrointestinal Neoplasms 1Gastrointestinal Diseases 1Gallbladder Neoplasms 1Fallopian Tube Neoplasms 1Digestive System Neoplasms 1Digestive System Diseases 1

Interventions

Ifosfamide 12Filgrastim 12Carboplatin 12Peripheral Blood Stem Cell Transplantation 11Etoposide 11Paclitaxel 9Cyclophosphamide 7Cisplatin 6Thiotepa 4Flow Cytometry 4Radiotherapy 3Immunologic Techniques 3pegfilgrastim 2etoposide phosphate 2Vinblastine 2Temozolomide 2Microarray Analysis 2Methylprednisolone 2Busulfan 2Alemtuzumab 2guadecitabine 1fludarabine phosphate 1dexamethasone acetate 1dexamethasone 21-phosphate 1Topotecan 1Tacrolimus 1Sunitinib 1Psychiatric Rehabilitation 1Prednisone 1Polymerase Chain Reaction 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Testicular Germ Cell Tumor × guadecitabine × Clear all
NCT02429466 2020-09-23

Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell Tumors

Indiana University

Phase 1 Completed
14 enrolled
Genitourinary

Testicular Germ Cell Tumor, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

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