Announcements Trials
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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Breast Neoplasms 6Triple Negative Breast Neoplasms 4Pancreatic Neoplasms 3Ovarian Neoplasms 2Neoplasm Metastasis 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myeloid, Acute 2Glioblastoma 2Thrombocythemia, Essential 1Testicular Neoplasms 1Small Cell Lung Carcinoma 1Renal Insufficiency 1Rectal Neoplasms 1Primary Myelofibrosis 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1Pathologic Complete Response 1Neoplasms, Unknown Primary 1Neoplasms 1Myelodysplastic-Myeloproliferative Diseases 1Melanoma 1Lung Neoplasms 1Liver Failure 1Leukemia, Myelomonocytic, Acute 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Hemangiosarcoma 1Head and Neck Neoplasms 1Gliosarcoma 1Glioma 1

Interventions

ruxolitinib 7fludarabine phosphate 3bomedemstat 3Whole-Body Irradiation 3Tacrolimus 3Specimen Handling 3Mycophenolic Acid 3Cyclophosphamide 3Biopsy 3fludarabine 2Stem Cell Transplantation 2Peripheral Blood Stem Cell Transplantation 2Methotrexate 2Melphalan 2Injections 2Busulfan 2venetoclax 1veliparib 1piperine 1pevonedistat 1iadademstat 1fedratinib 1demethoxycurcumin 1decitabine and cedazuridine drug combination 1anagrelide 1X-Rays 1Valganciclovir 1Transplantation 1Topotecan 1Therapeutics 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Thrombocythemia, Essential × veliparib × 1 year × Clear all
NCT03289910 2026-04-13

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

National Cancer Institute (NCI)

Phase 2 Active not recruiting
25 enrolled 15 charts
MyeloidOther hematologic neoplasm

Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

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