Announcements Trials
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Phase

Phase 2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Breast Neoplasms 7Triple Negative Breast Neoplasms 4Ovarian Neoplasms 4Glioblastoma 4Small Cell Lung Carcinoma 3Pancreatic Neoplasms 3Neoplasm Metastasis 3Gliosarcoma 3Fallopian Tube Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Astrocytoma 3Rectal Neoplasms 2Lymphoma, T-Cell 2Lymphoma, Mantle-Cell 2Glioma 2Colorectal Neoplasms 2Brain Neoplasms 2Waldenstrom Macroglobulinemia 1Uterine Cervical Neoplasms 1Thrombocythemia, Essential 1Squamous Cell Carcinoma of Head and Neck 1Skin Neoplasms 1Sezary Syndrome 1Prostatic Neoplasms 1Primary Myelofibrosis 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1Oropharyngeal Neoplasms 1Oligodendroglioma 1

Interventions

fludarabine phosphate 15Whole-Body Irradiation 9Peripheral Blood Stem Cell Transplantation 9Mycophenolic Acid 9Cyclophosphamide 8Busulfan 8Tacrolimus 7Cyclosporine 5ruxolitinib 4fludarabine 4Methotrexate 4Antilymphocyte Serum 411-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 3peginterferon alfa-2a 2givinostat hydrochloride 2givinostat 2Stem Cell Transplantation 2Radiotherapy 2Melphalan 2Etoposide 2Carboplatin 2veliparib 1thymoglobulin 1sonidegib 1pomalidomide 1merphos 1bomedemstat 1anagrelide 1Transplantation 1Topotecan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Thrombocythemia, Essential × veliparib × Clear all
NCT03289910 2026-04-13

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

National Cancer Institute (NCI)

Phase 2 Active not recruiting
25 enrolled 15 charts
MyeloidOther hematologic neoplasm

Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

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