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Phase

Phase 2 1

Status

Withdrawn 1Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 17Leukemia, Lymphocytic, Chronic, B-Cell 16Precursor Cell Lymphoblastic Leukemia-Lymphoma 15Hodgkin Disease 15Multiple Myeloma 12Lymphoma, Non-Hodgkin 11Myelodysplastic Syndromes 10Lymphoma, Mantle-Cell 10Myeloproliferative Disorders 9Leukemia, Myelomonocytic, Chronic 9Leukemia, Myeloid, Chronic-Phase 9Waldenstrom Macroglobulinemia 8Lymphoma, Large B-Cell, Diffuse 8Leukemia, Prolymphocytic 8Leukemia, Myelogenous, Chronic, BCR-ABL Positive 8Myelodysplastic-Myeloproliferative Diseases 6Lymphoma, Follicular 6Lymphoma, B-Cell, Marginal Zone 6Anemia, Refractory, with Excess of Blasts 6Leukemia 5Burkitt Lymphoma 5Recurrence 4Primary Myelofibrosis 4Lymphoma, Large-Cell, Immunoblastic 4Lymphoma 4Leukemia, Prolymphocytic, T-Cell 4Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 4Graft vs Host Disease 4Congenital Abnormalities 4Blast Crisis 4

Interventions

Peripheral Blood Stem Cell Transplantation 18fludarabine phosphate 17Cyclophosphamide 17Busulfan 12Tacrolimus 11Methotrexate 8Cyclosporine 8Antilymphocyte Serum 8Whole-Body Irradiation 7Mycophenolic Acid 7Filgrastim 6peginterferon alfa-2a 5Etoposide 5Prednisone 4Decitabine 4Cytarabine 4ruxolitinib 3fludarabine 3Radiotherapy 3Methylprednisolone 3Carboplatin 3Aspirin 3tipifarnib 2sonidegib 2merphos 2liposomal amphotericin B 2givinostat hydrochloride 2givinostat 2aldesleukin 2Transplantation 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Thrombocythemia, Essential × Cyclosporins × Clear all
NCT00397813 2020-01-31

Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

Fred Hutchinson Cancer Center

Phase 2 Completed
77 enrolled 16 charts
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Hemoglobinuria, Paroxysmal, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myelomonocytic, Chronic, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

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