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Phase

Phase NA 1Phase 1/2 1

Status

Completed 2Withdrawn 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 1Classical hematology 1

Conditions

Leukemia 14Leukemia, Myeloid, Acute 9Congenital Abnormalities 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Myelodysplastic Syndromes 5Leukemia, Myelomonocytic, Chronic 5Myeloproliferative Disorders 4Multiple Myeloma 4Lymphoma 4Leukemia, Myeloid, Chronic-Phase 4Leukemia, Lymphocytic, Chronic, B-Cell 4Anemia, Refractory, with Excess of Blasts 4Leukemia, Monocytic, Acute 3Leukemia, Megakaryoblastic, Acute 3Leukemia, Erythroblastic, Acute 3Blast Crisis 3Waldenstrom Macroglobulinemia 2Thrombocythemia, Essential 2Squamous Cell Carcinoma of Head and Neck 2Precancerous Conditions 2Polycythemia Vera 2Neoplasms, Plasma Cell 2Myelodysplastic-Myeloproliferative Diseases 2Monoclonal Gammopathy of Undetermined Significance 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Prolymphocytic 2

Interventions

Peripheral Blood Stem Cell Transplantation 18fludarabine phosphate 17Cyclophosphamide 17Busulfan 12Tacrolimus 11Methotrexate 8Cyclosporine 8Antilymphocyte Serum 8Whole-Body Irradiation 7Mycophenolic Acid 7Filgrastim 6peginterferon alfa-2a 5Etoposide 5Prednisone 4Decitabine 4Cytarabine 4ruxolitinib 3fludarabine 3Radiotherapy 3Methylprednisolone 3Carboplatin 3Aspirin 3tipifarnib 2sonidegib 2merphos 2liposomal amphotericin B 2givinostat hydrochloride 2givinostat 2aldesleukin 2Transplantation 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Thrombocythemia, Essential × Cytogenetic Analysis × Clear all
NCT00445744 2018-01-02

Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome

Fred Hutchinson Cancer Center

Phase NA Completed
52 enrolled 7 charts
MyeloidOther hematologic neoplasm

Chromosome 5q Deletion Syndrome, Congenital Abnormalities, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Primary Myelofibrosis

NCT00052520 2017-03-29

Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation

Fred Hutchinson Cancer Center

Phase 1/2 Completed
37 enrolled
Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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