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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gynecologic 1Gastrointestinal 1

Conditions

Leukemia, Myeloid, Acute 246Precursor Cell Lymphoblastic Leukemia-Lymphoma 147Myelodysplastic Syndromes 144Leukemia, Lymphocytic, Chronic, B-Cell 140Leukemia 128Multiple Myeloma 118Lymphoma 116Lymphoma, Non-Hodgkin 112Recurrence 79Hematologic Neoplasms 77Hodgkin Disease 68Melanoma 67Leukemia, Myelogenous, Chronic, BCR-ABL Positive 67Lymphoma, B-Cell 61Lymphoma, Mantle-Cell 52Lymphoma, Large B-Cell, Diffuse 50Lymphoma, Follicular 50Burkitt Lymphoma 41Ovarian Neoplasms 39Neoplasms 39Myeloproliferative Disorders 39Neoplasm Metastasis 33Lymphoma, B-Cell, Marginal Zone 30Graft vs Host Disease 29Neoplasms, Plasma Cell 28Carcinoma, Non-Small-Cell Lung 27Breast Neoplasms 27Leukemia, Biphenotypic, Acute 25Primary Myelofibrosis 24Anemia, Refractory, with Excess of Blasts 23

Interventions

pembrolizumab 3Drug Therapy 3Quality of Life 2Proton Therapy 2Immunotherapy 2Blood Specimen Collection 2ribociclib 1palbociclib 1napabucasin 1fludarabine 1epacadostat 1bosutinib 1amrubicin 1alovudine 1Tumor Burden 1Sunitinib 1Radiotherapy 1Radiosurgery 1Radiation 1Plicamycin 1Pemetrexed 1Patient Reported Outcome Measures 1Paclitaxel 1Nivolumab 1Molecular Diagnostic Techniques 1Magnetic Resonance Spectroscopy 1Histocompatibility Testing 1Fluorodeoxyglucose F18 1FAPI-46 1Everolimus 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Thymus Neoplasms × fludarabine × Clear all
NCT06885697 2026-02-17

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
100 enrolled
GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

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