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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gynecologic 1Gastrointestinal 1

Conditions

Leukemia, Myeloid, Acute 44Precursor Cell Lymphoblastic Leukemia-Lymphoma 29Myelodysplastic Syndromes 26Hematologic Neoplasms 20Lymphoma, Non-Hodgkin 19Multiple Myeloma 18Lymphoma 18Recurrence 15Lymphoma, B-Cell 14Lymphoma, Large B-Cell, Diffuse 13Leukemia, Lymphocytic, Chronic, B-Cell 12Burkitt Lymphoma 12Breast Neoplasms 11Pancreatic Neoplasms 10Ovarian Neoplasms 10Lymphoma, Follicular 10Neoplasm Metastasis 9Melanoma 9Leukemia, Myelomonocytic, Chronic 9Myeloproliferative Disorders 8Lymphoma, Mantle-Cell 7Lymphoma, B-Cell, Marginal Zone 7Leukemia, Biphenotypic, Acute 7Leukemia 7Hodgkin Disease 7Glioblastoma 7Carcinoma, Non-Small-Cell Lung 7Triple Negative Breast Neoplasms 6Stomach Neoplasms 6Osteosarcoma 6

Interventions

fludarabine 1Tumor Burden 1Quality of Life 1Proton Therapy 1Immunotherapy 1Histocompatibility Testing 1Everolimus 1Drug Therapy 1Cyclophosphamide 1Blood Specimen Collection 1177Lu-octreotide, DOTA(0)-Tyr(3)- 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Thymus Neoplasms × fludarabine × Clear all
NCT06885697 2026-06-05

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
100 enrolled
GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

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