Announcements Trials
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Phase

Phase 2 13Phase 1 5Phase EARLY_PHASE1 2Phase 2/3 2Phase NA 1

Status

Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 2Plasma cell 2Other hematologic neoplasm 2Myeloid 2Head & Neck 2Gynecologic 2Gastrointestinal 2Endocrine 2CNS 2Lymphoid 1Dermatologic 1

Conditions

Neoplasms 37Carcinoma, Non-Small-Cell Lung 29Prostatic Neoplasms 20Neoplasm Metastasis 19Breast Neoplasms 19Colorectal Neoplasms 17Squamous Cell Carcinoma of Head and Neck 14Leukemia, Myeloid, Acute 14Stomach Neoplasms 12Ovarian Neoplasms 12Melanoma 12Lung Neoplasms 12Carcinoma, Hepatocellular 12Recurrence 11Hematologic Neoplasms 10Endometrial Neoplasms 10Rectal Neoplasms 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Pancreatic Neoplasms 9Lymphoma 9Head and Neck Neoplasms 9Myasthenia Gravis 8Leukemia 8Urinary Bladder Neoplasms 7Neoplasms by Site 7Neoplasms by Histologic Type 7Lymphoma, Large B-Cell, Diffuse 7Glioblastoma 7Fatigue 6Colonic Neoplasms 6

Interventions

trametinib 1dabrafenib 1cobimetinib 1Vemurafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2/3 × Thyroid Carcinoma, Anaplastic × 1 year × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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