Clinical Trials

Phase 2 Active not recruiting

Thyroid Cancer, Papillary, Thyroid Neoplasms, Carcinoma, Medullary, Thyroid Carcinoma, Anaplastic

NCT05453799 2025-10-20

Vudalimab for the Treatment of Locally Advanced or Metastatic Anaplastic Thyroid Cancer or Hurthle Cell Thyroid Cancer

54 enrolled

Thyroid Carcinoma, Anaplastic

NCT06790706 2025-10-06

IMMUNORARE5

EndocrineGastrointestinalGynecologicHead & NeckNETThoracic

154 enrolled

Gastro-enteropancreatic neuroendocrine tumor, Carcinoid Tumor, Thymoma, Gestational Trophoblastic Disease, Thyroid Carcinoma, Anaplastic

NCT06374602 2025-09-05

Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer

20 enrolled

Phase 2 Active not recruiting

Thyroid Carcinoma, Anaplastic

NCT04238624 2025-07-02

Study of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid Cancer

16 enrolled

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT04400474 2025-06-19

CABATEN

CNSEndocrineHead & NeckNET

93 enrolled 17 charts

Adenocarcinoma, Paraganglioma, Pheochromocytoma, Neuroendocrine Tumors, Thyroid Carcinoma, Anaplastic

NCT04552769 2025-06-05

Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

9 enrolled 10 charts

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT02152137 2025-01-27

Inolitazone Dihydrochloride and Paclitaxel in Treating Patients With Advanced Anaplastic Thyroid Cancer

19 enrolled 13 charts

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT06235216 2024-11-01

SETHY

42 enrolled

Thyroid Carcinoma, Anaplastic

NCT03565536 2024-04-19

Nexavar for Neoadjuvant Treatment of Anaplastic Thyroid Cancer

18 enrolled

Thyroid Carcinoma, Anaplastic

NCT06362694 2024-04-12

Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy

10 enrolled

Thyroid Carcinoma, Anaplastic

NCT04739566 2024-03-25

ANAPLAST-NEO

Phase 2 Withdrawn

Thyroid Carcinoma, Anaplastic

NCT06079333 2023-10-12

NEO-ATACT

20 enrolled

Thyroid Carcinoma, Anaplastic

NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

206 enrolled 40 charts 4 FDA

CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

NCT01236547 2022-07-19

Intensity-Modulated Radiation Therapy and Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Anaplastic Thyroid Cancer

123 enrolled 24 charts

Thyroid Carcinoma, Anaplastic

NCT02688608 2022-02-10

Pembrolizumab in Anaplastic/Undifferentiated Thyroid Cancer

6 enrolled 10 charts

Thyroid Carcinoma, Anaplastic

NCT04574817 2020-10-05

Study of HX008 for the Treatment of Anaplastic Thyroid Cancer (ATC)

Phase 2 Unknown

66 enrolled

Thyroid Carcinoma, Anaplastic

NCT02726503 2020-06-17

HOPE

39 enrolled

Thyroid Carcinoma, Anaplastic

NCT03211117 2020-03-25

Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

3 enrolled 7 charts

Thyroid Carcinoma, Anaplastic

NCT00625846 2020-02-26

Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer

152 enrolled 16 charts

Thyroid Neoplasms, Carcinoma, Medullary, Thyroid Carcinoma, Anaplastic

NCT00654238 2019-11-18

Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid Cancer

59 enrolled 8 charts

Thyroid Neoplasms, Carcinoma, Medullary, Thyroid Carcinoma, Anaplastic

NCT02657369 2019-10-15

A Phase 2 Trial of Lenvatinib for the Treatment of Anaplastic Thyroid Cancer (ATC)

34 enrolled 13 charts

Thyroid Carcinoma, Anaplastic

NCT02289144 2019-07-30

Ceritinib in Mutation and Oncogene Directed Therapy in Thyroid Cancer

Phase 2 Withdrawn

Thyroid Carcinoma, Anaplastic

NCT03002623 2018-12-21

CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid Cancer

7 enrolled 13 charts

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00804830 2018-08-28

Avastin and Doxorubicin Postoperatively for Patients With Anaplastic Thyroid Cancer

15 enrolled

Carcinoma, Neoplasm Metastasis, Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00126568 2018-01-19

Sorafenib in Treating Patients With Advanced Anaplastic Thyroid Cancer

20 enrolled 10 charts

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00095836 2017-05-31

Gefitinib in Treating Patients With Locally Advanced or Metastatic Thyroid Cancer That Did Not Respond to Iodine Therapy

27 enrolled 16 charts

Thyroid Cancer, Papillary, Head and Neck Neoplasms, Thyroid Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Thyroid Carcinoma, Anaplastic

NCT01164176 2014-12-02

Everolimus in Treating Patients With Locally Advanced or Metastatic Thyroid Cancer

40 enrolled

Thyroid Cancer, Papillary, Head and Neck Neoplasms, Thyroid Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Thyroid Carcinoma, Anaplastic

NCT00115739 2014-04-21

Trial Evaluating Gleevec in Patients With Anaplastic Thyroid Carcinoma

11 enrolled 10 charts

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00095693 2014-01-16

Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally Recurrent Thyroid Cancer

25 enrolled

Thyroid Cancer, Papillary, Thyroid Neoplasms, Adenocarcinoma, Follicular, Thyroid Carcinoma, Anaplastic

NCT01118065 2013-08-12

Everolimus in Treating Patients With Progressive or Recurrent, Unresectable, or Metastatic Thyroid Cancer

Phase 2 Unknown

42 enrolled

Thyroid Cancer, Papillary, Head and Neck Neoplasms, Thyroid Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Thyroid Carcinoma, Anaplastic

NCT00002608 2013-07-10

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

CNSEndocrineGastrointestinalHead & NeckOther solid neoplasmSarcomaThoracic

30 enrolled

Familial ependymoma, Thyroid Cancer, Papillary, Mesothelioma, Malignant, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Medulloblastoma, Oligodendroglioma, Pheochromocytoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Carcinoma, Medullary, Glioma, Subependymal, Gliosarcoma, Optic Nerve Glioma, Thyroid Carcinoma, Anaplastic

NCT00004089 2013-07-10

Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer

Head and Neck Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00019331 2013-06-20

Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors

CNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Salivary Gland Neoplasms, Testicular Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma, Thyroid Carcinoma, Anaplastic

NCT00786552 2011-01-20

Panthera

Phase 2 Unknown

47 enrolled

Recurrence, Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00060242 2010-06-11

Combretastatin A4 Phosphate in Treating Patients With Advanced Anaplastic Thyroid Cancer

26 enrolled