Announcements Trials
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Phase

Phase 2 2Phase NA 1

Status

Completed 3

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Head & Neck 3Endocrine 2

Conditions

Carcinoma, Non-Small-Cell Lung 16Melanoma 8Lung Neoplasms 8Neoplasm Metastasis 6Colorectal Neoplasms 6Solid Tumours 5Neoplasms 5Breast Neoplasms 4Uveal Melanoma 3Thyroid Neoplasms 3Pancreatic Neoplasms 3Neurofibromatosis 1 3Colonic Neoplasms 3Thyroid Cancer, Papillary 2Carcinoma, Hepatocellular 2Biliary Tract Neoplasms 2Adult Solid Neoplasm 2Thyroid Diseases 1Thymoma 1Solid Tumors 1Small Cell Lung Carcinoma 1Sarcoma 1Renal Insufficiency 1Rectal Neoplasms 1Optic Nerve Glioma 1Non-small Cell Lung Cancer Metastatic 1Neurofibrosarcoma 1Neurofibroma, Plexiform 1Neuroblastoma 1Myelodysplastic-Myeloproliferative Diseases 1

Interventions

Iodine-131 11Thyrotropin Alfa 9Sorafenib 8lenvatinib 6Thyroidectomy 6vandetanib 5Sunitinib 5Saline Solution 5pazopanib 4Triiodothyronine 4Paclitaxel 4Magnetic Resonance Spectroscopy 4Vemurafenib 3Thyroxine 3Radiotherapy 3Everolimus 3Dexmedetomidine 3Control Groups 3Cisplatin 3AZD 6244 32-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 3trametinib 2tipifarnib 2romidepsin 2dabrafenib 2belinostat 2Trastuzumab 2Surveys and Questionnaires 2Surgical Procedures, Operative 2Immunohistochemistry 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Thyroid Neoplasms × AZD 6244 × Clear all
NCT02393690 2024-07-26

Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer

Academic and Community Cancer Research United

Phase 2 Completed
60 enrolled 12 charts
EndocrineHead & Neck

Thyroid Cancer, Papillary, Thyroid Neoplasms, Adenocarcinoma, Follicular

NCT00970359 2017-04-12

Reacquisition of Radioactive Iodine (RAI) Uptake of RAI-Refractory Metastatic Thyroid Cancers by Pretreatment With the Selective MEK Inhibitor AZD6244

Memorial Sloan Kettering Cancer Center

Phase NA Completed
24 enrolled 8 charts
Head & Neck

Neoplasm Metastasis, Thyroid Diseases, Thyroid Neoplasms

NCT00559949 2017-01-30

Selumetinib in Treating Patients With Papillary Thyroid Cancer That Did Not Respond to Radioactive Iodine

National Cancer Institute (NCI)

Phase 2 Completed
39 enrolled 8 charts
EndocrineHead & Neck

Thyroid Cancer, Papillary, Thyroid Neoplasms

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