Announcements Trials
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Phase

Phase 2 3Phase 4 1Phase 3 1

Status

Completed 5

Sponsor Class

INDUSTRY 5OTHER 1NIH 1NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Head & Neck 5Endocrine 2

Conditions

Carcinoma, Non-Small-Cell Lung 13Neoplasm Metastasis 10Carcinoma, Medullary 10Thyroid Neoplasms 5Lung Neoplasms 5Prostatic Neoplasms 3Neoplasms 3Adenocarcinoma 3Familial medullary thyroid carcinoma 2Colorectal Neoplasms 2Carcinoma, Squamous Cell 2Breast Neoplasms 2Recurrence 1Rectal Neoplasms 1Pleural Effusion 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Multiple Myeloma 1Mesothelioma 1Head and Neck Neoplasms 1Gallbladder Neoplasms 1Differentiated Thyroid Cancer 1Colonic Neoplasms 1Cholangiocarcinoma 1Carcinoma, Large Cell 1Carcinoma, Hepatocellular 1Carcinoma 1Biliary Tract Neoplasms 1Aggression 1Advanced Breast Cancer 1

Interventions

lenvatinib 9vandetanib 5pembrolizumab 4Sorafenib 4selpercatinib 3Thyrotropin Alfa 3trametinib 2fosbretabulin 2combretastatin 2cabozantinib 2belinostat 2Paclitaxel 2Gemcitabine 2Fluorouracil 2Cetuximab 2Carboplatin 2Axitinib 2130-nm albumin-bound paclitaxel 2ulixertinib 1trastuzumab deruxtecan 1tipifarnib 1surufatinib 1repotrectinib 1pralsetinib 1naporafenib 1motesanib diphosphate 1methyl N-acetylsibirosaminide 1larotrectinib 1irofulven 1durvalumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × Thyroid Neoplasms × vandetanib × Clear all
NCT01496313 2025-10-03

To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid Cancer

Sanofi

Phase 4 Completed
81 enrolled 15 charts
Head & Neck

Neoplasm Metastasis, Thyroid Neoplasms, Carcinoma, Medullary

NCT00410761 2025-09-24

An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer

Sanofi

Phase 3 Completed
331 enrolled 15 charts
EndocrineHead & Neck

Familial medullary thyroid carcinoma, Thyroid Neoplasms, Carcinoma, Medullary

NCT00537095 2024-04-19

Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer

Sanofi

Phase 2 Completed
164 enrolled 10 charts
Head & Neck

Thyroid Neoplasms

NCT00098345 2018-05-07

Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer

Sanofi

Phase 2 Completed
40 enrolled 12 charts
Head & Neck

Thyroid Neoplasms

NCT00358956 2017-01-30

A Study To Assess ZD6474 (ZACTIMAâ„¢) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer

Sanofi

Phase 2 Completed
19 enrolled 10 charts
EndocrineHead & Neck

Familial medullary thyroid carcinoma, Thyroid Neoplasms, Carcinoma, Medullary

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