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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Active not recruiting 2Recruiting 1Not yet recruiting 1

Sponsor Class

INDUSTRY 2OTHER 1NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Breast 4

Conditions

Breast Neoplasms 57Neoplasm Metastasis 21Carcinoma, Non-Small-Cell Lung 9Stomach Neoplasms 8Brain Neoplasms 8Colorectal Neoplasms 7Triple Negative Breast Neoplasms 4Pancreatic Neoplasms 4Ovarian Neoplasms 4Endometrial Neoplasms 4Salivary Gland Neoplasms 3Recurrence 3Neoplasms 3Esophageal Neoplasms 3Adenocarcinoma 3Prostatic Neoplasms 2Meningeal Carcinomatosis 2HER2-positive Gastric Cancer 2Colonic Neoplasms 2Breast Cancer With Brain Metastasis 2Advanced Solid Tumor 2Advanced Breast Cancer 2Adenocarcinoma Of Esophagus 2Vulvar Neoplasms 1Vaginal Neoplasms 1Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Urethral Neoplasms 1Unresectable Locally Recurrent Breast Cancer 1

Interventions

pembrolizumab 96Carboplatin 67Paclitaxel 56Cyclophosphamide 40Capecitabine 30Specimen Handling 28sacituzumab govitecan 26130-nm albumin-bound paclitaxel 25Gemcitabine 22Magnetic Resonance Spectroscopy 21olaparib 20Doxorubicin 20Albumin-Bound Paclitaxel 20Taxes 19Biopsy 19Drug Therapy 16atezolizumab 14Nivolumab 14toripalimab 12Radiotherapy 12Epirubicin 12durvalumab 11Docetaxel 10Cisplatin 10Bevacizumab 10eribulin 9fludarabine 8Standard of Care 7Radiation 7Injections 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Triple Negative Breast Neoplasms × trastuzumab deruxtecan × 1 year × Clear all
NCT07137416 2026-05-28

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

National Cancer Institute (NCI)

Phase 1 Recruiting
36 enrolled
Breast

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT03742102 2026-04-24

BEGONIA

AstraZeneca

Phase 1/2 Active not recruiting
243 enrolled 13 charts
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04556773 2025-12-17

DB-08

AstraZeneca

Phase 1 Active not recruiting
138 enrolled
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07151586 2025-09-03

ALTER

UNICANCER

Phase 2 Not yet recruiting
260 enrolled
Breast

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

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