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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Breast 1

Conditions

Leukemia, Myeloid, Acute 17Myelodysplastic Syndromes 9Leukemia, Myelomonocytic, Chronic 4Myeloproliferative Disorders 3Myelodysplastic-Myeloproliferative Diseases 2Leukemia, Biphenotypic, Acute 2Triple Negative Breast Neoplasms 1Thrombocythemia, Essential 1Systemic Mastocytosis With an Associated Hematologic Neoplasm 1Primary Myelofibrosis 1Polycythemia Vera 1Mesothelioma, Malignant 1Mesothelioma 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, B-Cell 1Hodgkin Disease 1GATA2 Deficiency 1Cytopenia 1Central Nervous System Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Carcinoma, Merkel Cell 1BRCA1 Mutation 1Anemia, Refractory, with Excess of Blasts 1Allogeneic Stem Cell Transplantation 1

Interventions

pembrolizumab 47Carboplatin 35Paclitaxel 28Specimen Handling 20Cyclophosphamide 17Capecitabine 16Magnetic Resonance Spectroscopy 15sacituzumab govitecan 13Gemcitabine 13Biopsy 13Taxes 12130-nm albumin-bound paclitaxel 11Albumin-Bound Paclitaxel 9olaparib 8Doxorubicin 8Nivolumab 7fludarabine 6Cisplatin 6eribulin 5atezolizumab 5Radiotherapy 5Docetaxel 5durvalumab 4Immunoglobulin G 4Fulvestrant 4Epirubicin 4Drug Therapy 4Bevacizumab 4veliparib 3toripalimab 3

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Triple Negative Breast Neoplasms × decitabine and cedazuridine drug combination × 90 days × Clear all
NCT05673200 2026-05-13

Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

National Cancer Institute (NCI)

Phase 1 Recruiting
32 enrolled
Breast

Triple Negative Breast Neoplasms

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