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Phase

Phase 2 2Phase EARLY_PHASE1 1Phase 1 1

Status

Terminated 3Completed 1

Sponsor Class

OTHER 2NIH 2

Study Type

Interventional 4

Sponsor

Cancer Type

Breast 4

Conditions

Breast Neoplasms 24Carcinoma, Non-Small-Cell Lung 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Pancreatic Neoplasms 5Neoplasms 5Lung Neoplasms 5Leukemia, Myeloid, Acute 5Triple Negative Breast Neoplasms 4Melanoma 4Leukemia, Myelomonocytic, Chronic 4Carcinoma, Renal Cell 4Breast Diseases 4Urinary Bladder Neoplasms 3Thoracic Neoplasms 3Respiratory Tract Neoplasms 3Lymphoma 3Lung Diseases 3Leukemia, Myelomonocytic, Acute 3Kidney Neoplasms 3Fallopian Tube Neoplasms 3Congenital Abnormalities 3Colonic Neoplasms 3Bronchial Neoplasms 3Vulvar Neoplasms 2Vaginal Neoplasms 2Uveal Melanoma 2Uterine Cervical Neoplasms 2Sezary Syndrome 2Recurrence 2Rectal Neoplasms 2

Interventions

pembrolizumab 161Carboplatin 145Paclitaxel 125Cyclophosphamide 94130-nm albumin-bound paclitaxel 66Capecitabine 64Gemcitabine 54Doxorubicin 50Albumin-Bound Paclitaxel 45Taxes 42atezolizumab 41Cisplatin 38sacituzumab govitecan 34Nivolumab 34olaparib 32Epirubicin 32Specimen Handling 28Docetaxel 28eribulin 27Bevacizumab 26durvalumab 25Drug Therapy 25Biopsy 24camrelizumab 23Magnetic Resonance Spectroscopy 22toripalimab 19Radiotherapy 17spartalizumab 16Everolimus 15veliparib 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Triple Negative Breast Neoplasms × entinostat × Clear all
NCT01349959 2025-04-27

Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer

National Cancer Institute (NCI)

Phase 2 Completed
58 enrolled 16 charts
Breast

Breast Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT03361800 2024-03-25

Window of Opportunity Trial of Entinostat in Patients With Newly Diagnosed Stage I-IIIC,TNBC

UNC Lineberger Comprehensive Cancer Center

Phase EARLY_PHASE1 Terminated
5 enrolled
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01234532 2022-05-03

0927GCC

University of Maryland, Baltimore

Phase 2 Terminated
5 enrolled 7 charts
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04296942 2022-01-11

BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
1 enrolled 10 charts
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

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