Clinical Trials Browser

Creatine deficiency, X-linked, Telomeric 22q13 Monosomy Syndrome, Chromosome 15q, partial deletion, Fragile X Syndrome, Hamartoma Syndrome, Multiple, Tuberous Sclerosis, Rett Syndrome, Angelman Syndrome

NCT05104983 2026-01-22

TSC-STEPS

Phase 2 Recruiting

64 enrolled

Epilepsy, Tuberous Sclerosis

NCT05467397 2026-01-21

Feasibility of [11C]Acetate-PET in LAM and TSC

Phase 1/2 Active not recruiting

7 enrolled 6 charts

Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT07287202 2025-12-23

Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME)

Phase 1/2 Not yet recruiting

15 enrolled

Focal Cortical Dysplasia, Tuberous Sclerosis, Hemimegalencephaly

NCT05626634 2025-12-03

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Phase 2 Completed

41 enrolled

CDKL5 deficiency disorder, Epilepsy, Epilepsies, Myoclonic, Tuberous Sclerosis, Lennox Gastaut Syndrome

NCT03363763 2025-12-01

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Phase 2 Terminated

24 enrolled 11 charts

Erythema, Exanthema, Fibroma, Tuberous Sclerosis, Facies

NCT06965881 2025-11-21

Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults

Phase 1 Terminated

30 enrolled

Focal Cortical Dysplasia, Tuberous Sclerosis

NCT06975605 2025-11-18

Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.

Phase 1 Completed

18 enrolled

Focal Cortical Dysplasia, Tuberous Sclerosis

NCT04485104 2025-10-31

Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures

Phase 3 Terminated

3 enrolled 28 charts

Tuberous Sclerosis 1, Tuberous Sclerosis 2, Epilepsy, Epilepsies, Myoclonic, Seizures, Spasms, Infantile, Tuberous Sclerosis, Lennox Gastaut Syndrome

NCT05604170 2025-10-01

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

Phase 3 Terminated

117 enrolled 11 charts

Tuberous Sclerosis

NCT06879665 2025-09-22

TANDem-2

Phase NA Enrolling by invitation

30 enrolled

Tuberous Sclerosis

NCT03836300 2025-07-31

Parent and Infant Inter(X)Action Intervention (PIXI)

Phase NA Enrolling by invitation

120 enrolled

Telomeric 22q13 Monosomy Syndrome, Developmental Disabilities, DiGeorge Syndrome, Down Syndrome, Fragile X Syndrome, Klinefelter Syndrome, Prader-Willi Syndrome, Tuberous Sclerosis, Turner Syndrome, Rett Syndrome, Angelman Syndrome, Williams Syndrome, Muscular Dystrophy, Duchenne, Smith-Magenis Syndrome

NCT06081348 2025-07-16

CALM

Phase 2 Recruiting

130 enrolled

Autism Spectrum Disorder, Anxiety Disorders, Attention Deficit Disorder with Hyperactivity, Autistic Disorder, DiGeorge Syndrome, Fragile X Syndrome, Tourette Syndrome, Tic Disorders, Tuberous Sclerosis, 22q11 Deletion Syndrome, Neurodevelopmental Disorders

NCT05323734 2025-07-11

Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy

Phase 3 Completed

129 enrolled 13 charts

Tuberous Sclerosis

NCT05059327 2025-06-04

Basimglurant (NOE-101) in Children, Adolescents, and Young Adults With TSC

Phase 2 Completed

61 enrolled

Seizures, Tuberous Sclerosis