Clinical Trials Browser

Tuberous Sclerosis × Everolimus × Clear all

NCT02962414 2026-04-02

Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

Phase 3 Active not recruiting

Seizures, Tuberous Sclerosis

NCT05252585 2026-04-02

A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

Phase 4 Active not recruiting

Tuberous Sclerosis, Angiomyolipoma

NCT07369505 2026-01-27

Sapu003 in Advanced mTOR-sensitive Solid Tumors

Phase 1 Recruiting

EndocrineGastrointestinalGenitourinaryNET

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Tuberous Sclerosis, Neuroendocrine Tumors

NCT03525834 2021-09-09

Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.

Phase 4 Completed

40 enrolled 10 charts

Tuberous Sclerosis, Lymphangioleiomyomatosis, Angiomyolipoma

NCT02451696 2021-09-01

A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD

Phase 2 Completed

15 enrolled 9 charts

Focal Cortical Dysplasia, Epilepsy, Tuberous Sclerosis

NCT02860494 2021-05-03

EVEROST

Phase 2/3 Withdrawn

Tuberous Sclerosis

NCT01929642 2021-03-29

RAPT

Phase 2 Completed

3 enrolled 10 charts

Autistic Disorder, Tuberous Sclerosis, Self-Injurious Behavior

NCT02201212 2020-09-16

Everolimus for Cancer With TSC1 or TSC2 Mutation

Phase 2 Completed

30 enrolled 12 charts

Tuberous Sclerosis

NCT02061397 2020-08-25

SOS

Phase 1/2 Completed

10 enrolled 6 charts

Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT01954693 2018-01-30

TRON

Phase 2 Unknown

Tuberous Sclerosis

NCT01289912 2018-01-25

TSC

Phase 2 Completed

52 enrolled 12 charts

Autistic Disorder, Tuberous Sclerosis

NCT01070316 2017-03-13

Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)

Phase 1/2 Completed

20 enrolled 8 charts

Epilepsy, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT00790400 2017-02-17

EXIST-2

Phase 3 Completed

118 enrolled 15 charts

Tuberous Sclerosis 2, Astrocytoma, Hereditary Sensory and Autonomic Neuropathies, Seizures, Tuberous Sclerosis, Lymphangioleiomyomatosis, Angiomyolipoma

NCT00789828 2016-02-03

EXIST-1

Phase 3 Completed

117 enrolled 15 charts

Astrocytoma, Tuberous Sclerosis

NCT01730209 2015-05-05

RAPIT

Phase 2/3 Unknown

Autistic Disorder, Intellectual Disability, Tuberous Sclerosis

NCT00411619 2014-10-20

Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex

Phase 1/2 Completed

28 enrolled 7 charts

Astrocytoma, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT00457964 2013-09-25

RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM

Phase 1/2 Completed

Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT00792766 2013-09-18

Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)

Phase 1/2 Completed

Tuberous Sclerosis, Angiolipoma