Announcements Trials
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Phase

Phase 2 7Phase 3 2Phase 2/3 2Phase 1/2 2Phase 1 2

Status

Completed 4Unknown 1Terminated 1Recruiting 1

Sponsor Class

OTHER 6INDUSTRY 1

Study Type

Interventional 7

Sponsor

Conditions

Leukemia, Myeloid, Acute 21Precursor Cell Lymphoblastic Leukemia-Lymphoma 20Myelodysplastic Syndromes 19Lymphoma, Non-Hodgkin 17Leukemia, Lymphocytic, Chronic, B-Cell 15Hodgkin Disease 15Graft vs Host Disease 13Lymphoma, Mantle-Cell 12Leukemia 12Multiple Myeloma 11Lymphoma, Large B-Cell, Diffuse 11Sarcoma 10Lymphoma 10Lymphoma, Follicular 9Lymphoma, B-Cell, Marginal Zone 9Burkitt Lymphoma 9Myeloproliferative Disorders 8Waldenstrom Macroglobulinemia 7Tuberous Sclerosis 7Neoplasms 7Leukemia, Myelogenous, Chronic, BCR-ABL Positive 7Hematologic Neoplasms 7Congenital Abnormalities 7Primary Myelofibrosis 6Lymphoma, Large-Cell, Immunoblastic 6Leukemia, Myelomonocytic, Chronic 6Leukemia, Myeloid, Chronic-Phase 6Leukemia, Myeloid, Accelerated Phase 6Breast Neoplasms 6Osteosarcoma 5

Interventions

Sirolimus 7Everolimus 5ganaxolone 1dactolisib 1Vigabatrin 1Sertraline 1Selective Serotonin Reuptake Inhibitors 1Propranolol 1Aspirin 1Anticonvulsants 12-chloro-4-(1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl)pyridine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Phase 2 × Tuberous Sclerosis × Sirolimus × Clear all
NCT05104983 2026-01-22

TSC-STEPS

Children's Hospital Medical Center, Cincinnati

Phase 2 Recruiting
64 enrolled

Epilepsy, Tuberous Sclerosis

NCT03363763 2025-12-01

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

Aucta Pharmaceuticals, Inc

Phase 2 Terminated
24 enrolled 11 charts

Erythema, Exanthema, Fibroma, Tuberous Sclerosis, Facies

NCT00126672 2022-04-25

RAPAMYCIN FOR KIDNEY ANGIOMYOLIPOMAS

Dana-Farber Cancer Institute

Phase 2 Completed
36 enrolled 8 charts

Neoplasms, Tuberous Sclerosis, Angiomyolipoma

NCT01929642 2021-03-29

RAPT

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Phase 2 Completed
3 enrolled 10 charts

Autistic Disorder, Tuberous Sclerosis, Self-Injurious Behavior

NCT01526356 2020-10-26

Treatment

The University of Texas Health Science Center, Houston

Phase 2 Completed
179 enrolled 13 charts

Tuberous Sclerosis, Angiofibroma

NCT00490789 2008-04-30

TESSTAL

Cardiff University

Phase 2 Unknown
14 enrolled

Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT00457808 2007-04-09

Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM

Children's Hospital Medical Center, Cincinnati

Phase 2 Completed
25 enrolled

Tuberous Sclerosis, Lymphangioleiomyomatosis

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