Clinical Trials

84 enrolled 16 charts

Tuberous Sclerosis

NCT04595513 2024-05-16

STOP2

5 enrolled 15 charts

Epilepsy, Tuberous Sclerosis

NCT01906866 2024-04-23

Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities

125 enrolled 22 charts

Autism Spectrum Disorder, Sleep Wake Disorders, Tuberous Sclerosis, Angelman Syndrome, Parasomnias, Smith-Magenis Syndrome

NCT03276195 2023-11-29

Studies in Patients With Tuberous Sclerosis Complex

32 enrolled

Tuberous Sclerosis, Neurodevelopmental Disorders

NCT03826628 2023-09-08

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Phase 2/3 Completed

107 enrolled 24 charts

Tuberous Sclerosis

NCT04285346 2023-04-04

TSC

23 enrolled 9 charts

Tuberous Sclerosis

NCT05323370 2023-03-29

LAM-CAK

19 enrolled

Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT02544763 2022-09-28

A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

224 enrolled 18 charts

Seizures, Tuberous Sclerosis

NCT02325505 2022-08-04

Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma

200 enrolled

Tuberous Sclerosis, Lymphangioleiomyomatosis, Angiomyolipoma

NCT02544750 2022-07-14

An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

199 enrolled 14 charts

Seizures, Tuberous Sclerosis

NCT00126672 2022-04-25

RAPAMYCIN FOR KIDNEY ANGIOMYOLIPOMAS

36 enrolled 8 charts

Neoplasms, Tuberous Sclerosis, Angiomyolipoma

NCT03525834 2021-09-09

Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.

Phase 4 Completed

40 enrolled 10 charts

Tuberous Sclerosis, Lymphangioleiomyomatosis, Angiomyolipoma

NCT02451696 2021-09-01

A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD

15 enrolled 9 charts

Focal Cortical Dysplasia, Epilepsy, Tuberous Sclerosis

NCT01929642 2021-03-29

RAPT

3 enrolled 10 charts

Autistic Disorder, Tuberous Sclerosis, Self-Injurious Behavior

NCT03650452 2021-02-18

ELEKTRA

141 enrolled 24 charts

CDKL5 deficiency disorder, Brain Diseases, Central Nervous System Diseases, Epilepsy, Epilepsies, Myoclonic, Nervous System Diseases, Seizures, Spasms, Infantile, Tuberous Sclerosis, Hypoxia-Ischemia, Brain, Malformations of Cortical Development, Lennox Gastaut Syndrome

NCT01780441 2021-02-04

Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)

166 enrolled

Autistic Disorder, Tuberous Sclerosis

NCT01526356 2020-10-26

Treatment

179 enrolled 13 charts

Tuberous Sclerosis, Angiofibroma

NCT02201212 2020-09-16

Everolimus for Cancer With TSC1 or TSC2 Mutation

30 enrolled 12 charts

Tuberous Sclerosis

NCT02061397 2020-08-25

SOS

10 enrolled 6 charts

Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT01767779 2019-04-11

Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC

40 enrolled

Epilepsy, Seizures, Tuberous Sclerosis

NCT00552955 2019-03-06

Effect of Fasting on the Size of Abdominal Lymphatic Tumors in Women

35 enrolled

Ascites, Lymphangiomyoma, Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT02634931 2019-02-20

Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex

94 enrolled

Tuberous Sclerosis, Angiofibroma, Plaque, Amyloid

NCT02687633 2018-05-02

Early Behavioral Intervention to Improve Social Communication Function in Infants With Tuberous Sclerosis Complex

Phase NA Completed

8 enrolled

Tuberous Sclerosis

NCT01289912 2018-01-25

TSC

52 enrolled 12 charts

Autistic Disorder, Tuberous Sclerosis

NCT00598455 2017-05-04

Tuberous Sclerosis Complex Natural History Study: Renal Manifestations

450 enrolled

Tuberous Sclerosis

NCT03140449 2017-05-04

Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis

52 enrolled

Tuberous Sclerosis

NCT01070316 2017-03-13

Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)

20 enrolled 8 charts

Epilepsy, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT00790400 2017-02-17

EXIST-2

118 enrolled 15 charts

Tuberous Sclerosis 2, Astrocytoma, Hereditary Sensory and Autonomic Neuropathies, Seizures, Tuberous Sclerosis, Lymphangioleiomyomatosis, Angiomyolipoma

NCT02635789 2017-02-02

Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)

62 enrolled

Tuberous Sclerosis, Angiofibroma, Plaque, Amyloid

NCT01853423 2016-08-19

Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream

Phase 1 Completed

11 enrolled

Tuberous Sclerosis, Angiofibroma

NCT00789828 2016-02-03

EXIST-1

117 enrolled 15 charts

Astrocytoma, Tuberous Sclerosis

NCT00989742 2015-12-02

Doxycycline In Lymphangioleiomyomatosis (LAM)

Phase 4 Completed

24 enrolled

Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT00411619 2014-10-20

Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex

28 enrolled 7 charts