Announcements Trials
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Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Withdrawn 1Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 1NIH 1INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 3Thoracic 1Other solid neoplasm 1Other hematologic neoplasm 1Lymphoid 1Genitourinary 1Dermatologic 1CNS 1

Conditions

Melanoma 68Carcinoma, Non-Small-Cell Lung 41Carcinoma, Renal Cell 36Neoplasm Metastasis 22Carcinoma, Hepatocellular 15Neoplasms 14Colorectal Neoplasms 13Brain Neoplasms 13Skin Neoplasms 12Squamous Cell Carcinoma of Head and Neck 11Pancreatic Neoplasms 10Lung Neoplasms 10Kidney Neoplasms 10Uveal Melanoma 9Ovarian Neoplasms 9Urinary Bladder Neoplasms 8Sarcoma 8Prostatic Neoplasms 8Carcinoma, Transitional Cell 8Mesothelioma 7Glioblastoma 7Clear-cell metastatic renal cell carcinoma 7Carcinoma, Merkel Cell 7Recurrence 6Colonic Neoplasms 6Triple Negative Breast Neoplasms 5Small Cell Lung Carcinoma 5Myelodysplastic Syndromes 5Multiple Myeloma 5Mesothelioma, Malignant 5

Interventions

pembrolizumab 8Nivolumab 6Ipilimumab 3toripalimab 2atezolizumab 2Specimen Handling 2Celecoxib 2relatlimab 1fludarabine phosphate 1fludarabine 1durvalumab 1denileukin diftitox 1camrelizumab 1avelumab 1XELOX 1Neoadjuvant Therapy 1Magnetic Resonance Spectroscopy 1Irinotecan 1Interleukin-2 1Induction Chemotherapy 1Immunotherapy 1Immune Checkpoint Inhibitors 1IMM-101 1E7777 fusion protein 1Docetaxel 1Diffusion Tensor Imaging 1DNA Mismatch Repair 1DEAE-Dextran 1Cyclophosphamide 1Colonoscopy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Turcot syndrome × Ipilimumab × 1 year × Clear all
NCT06362369 2026-04-13

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

7 Hills Pharma, LLC

Phase 1/2 Recruiting
126 enrolled
DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

Turcot syndrome, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Melanoma, Neoplasm Metastasis, Skin Neoplasms, Colorectal Neoplasms

NCT07403877 2026-02-11

TORCH-OPTIMA

Fudan University

Phase 2 Not yet recruiting
114 enrolled
Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT04500548 2025-09-10

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

National Cancer Institute (NCI)

Phase 1 Withdrawn
CNSGastrointestinalLymphoidOther hematologic neoplasm

Turcot syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Lymphoma, Neuroblastoma, Xeroderma Pigmentosum, Central Nervous System Neoplasms, Hematologic Neoplasms

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