Clinical Trials Browser

NCT07625735 2026-06-04

MMR Status Modulates the Predictive Value of Lymphatic Invasion for Lymph Node Metastasis in Gastric Cancer

Not yet recruiting

3,000 enrolled

Turcot syndrome, Lymphatic Metastasis

NCT03935893 2026-06-01

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Phase 2 Active not recruiting

20 enrolled

DermatologicEndocrineGastrointestinalNETOther solid neoplasmSarcomaThoracic

Turcot syndrome, Mesothelioma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Neuroendocrine Tumors, Microsatellite Instability

NCT05200559 2026-05-29

T-regulatory Cell Depletion With E7777 Combined With Pembrolizumab in Recurrent or Metastatic Solid Tumors

Phase 1/2 Active not recruiting

25 enrolled

Gynecologic

Turcot syndrome, Carcinoma, Ovarian Epithelial

NCT05426005 2026-05-22

Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer

Phase 1/2 Recruiting

28 enrolled

Gastrointestinal

Turcot syndrome, Diabetes Mellitus, Insulin-Dependent, 12, Colorectal Neoplasms

NCT06903858 2026-05-22

PICC-3

Phase 2 Recruiting

105 enrolled

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT06708429 2026-04-24

LYNX-EYE

Recruiting

300 enrolled

GastrointestinalGynecologic

Turcot syndrome, Lynch syndrome I (site-specific colonic cancer), Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Colorectal Neoplasms, Endometrial Neoplasms, Lynch Syndrome II

NCT03050268 2026-04-23

SJFAMILY

Recruiting

1,500 enrolled

BreastCNSClassical hematologyDermatologicEndocrineGastrointestinalGynecologicLymphoidOther solid neoplasmSarcoma

Turcot syndrome, Juvenile polyposis syndrome, Choroid Plexus Carcinoma, GATA2 Deficiency, Basal Cell Nevus Syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Fanconi Anemia, Hamartoma Syndrome, Multiple, von Hippel-Lindau Disease, Hodgkin Disease, Lymphoma, Non-Hodgkin, Melanoma, Neuroblastoma, Neurofibromatosis 1, Noonan Syndrome, Pancreatic Neoplasms, Paraganglioma, Peutz-Jeghers Syndrome, Pheochromocytoma, Rothmund-Thomson Syndrome, Adenomatous Polyposis Coli, Retinoblastoma, Rhabdomyosarcoma, Tuberous Sclerosis, Neurofibromatosis 2, Li-Fraumeni Syndrome, Adrenocortical Carcinoma, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2a, Dyskeratosis Congenita, Genetic Predisposition to Disease, Anemia, Diamond-Blackfan, Carney Complex, Hereditary Breast and Ovarian Cancer Syndrome

NCT03607890 2026-03-16

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Phase 2 Active not recruiting

38 enrolled

Turcot syndrome, Microsatellite Instability

NCT07461246 2026-03-10

RIPAF

Active not recruiting

1,500 enrolled

GastrointestinalSarcoma

Turcot syndrome, Attenuated familial adenomatous polyposis, Polyposis Syndrome, Hereditary Mixed, 1, Gardner Syndrome, Neoplastic Syndromes, Hereditary, Adenomatous Polyposis Coli, Colorectal Neoplasms, Desmoid Tumors

NCT07450612 2026-03-04

BEACON

Recruiting

1,200 enrolled

Gastrointestinal

Turcot syndrome, Lynch syndrome I (site-specific colonic cancer), Colonic Diseases, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms, Lynch Syndrome II

NCT07403877 2026-02-11