Announcements Trials
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Phase

Phase 1 6Phase 1/2 2

Status

Completed 5Terminated 1

Sponsor Class

OTHER 4NIH 2

Study Type

Interventional 6

Sponsor

Cancer Type

Other solid neoplasm 6

Conditions

Ovarian Neoplasms 21Neoplasms 16Neuroblastoma 14Small Cell Lung Carcinoma 13Carcinoma, Ovarian Epithelial 12Fallopian Tube Neoplasms 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Lung Neoplasms 10Recurrence 8Leukemia 8Leukemia, Myeloid, Acute 7Uterine Cervical Neoplasms 6Unspecified Adult Solid Tumor, Protocol Specific 6Neoplasm Metastasis 6Lymphoma 6Sarcoma, Ewing 5Endometrial Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Brain Neoplasms 5Sarcoma 4Lymphoma, Follicular 4Glioma 4Central Nervous System Neoplasms 4Burkitt Lymphoma 4Blast Crisis 4Rhabdomyosarcoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Myelodysplastic Syndromes 3Meningeal Carcinomatosis 3Medulloblastoma 3

Interventions

Irinotecan 30Gemcitabine 25Paclitaxel 24Cisplatin 24Docetaxel 19Oxaliplatin 15Fluorouracil 15alvocidib 13Leucovorin 13Carboplatin 12Capecitabine 12Bortezomib 10Taxes 83-aminopyridine-2-carboxaldehyde thiosemicarbazone 7ixabepilone 6Vorinostat 6Topotecan 6Temozolomide 6Immunohistochemistry 6Immunoenzyme Techniques 6Bevacizumab 67-hydroxystaurosporine 6tanespimycin 5Sorafenib 5Pharmacogenomic Testing 5Pemetrexed 5Etoposide 5Chromatography, High Pressure Liquid 57-cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine 5temsirolimus 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 1 × Unspecified Adult Solid Tumor, Protocol Specific × Topotecan × Clear all
NCT00541359 2017-08-09

Bortezomib and Topotecan Hydrochloride in Treating Patients With Advanced Solid Tumors

City of Hope Medical Center

Phase 1 Completed
54 enrolled
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00002948 2014-07-02

High-Dose Topotecan and Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Yale University

Phase 1 Terminated
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003198 2013-06-27

Ifosfamide and Topotecan in Treating Patients With Refractory Solid Tumors

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00002587 2013-06-03

Paclitaxel Plus Topotecan in Treating Patients With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
20 enrolled
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00068484 2013-02-01

A Dose Finding Phase I Trial of the Combination of Topotecan and PS-341, a Novel Proteasome Inhibitor, in Advanced Malignancies

National Cancer Institute (NCI)

Phase 1 Completed
25 enrolled
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00005990 2012-11-09

R115777 Plus Topotecan in Treating Patients With Advanced Solid Tumors

NYU Langone Health

Phase 1 Completed
Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

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