Clinical Trials

Urinary Bladder Neoplasms

NCT04902040 2026-04-30

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Phase 1/2 Terminated

19 enrolled 11 charts

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Lung Neoplasms

NCT03317158 2026-04-15

ADAPT-BLADDER

55 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT06704191 2026-03-30

In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

40 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT06470282 2026-02-18

Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer

47 enrolled

Urinary Bladder Neoplasms

NCT07410676 2026-02-18

EBNK-ST-001

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT02989584 2026-01-07

A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer

54 enrolled

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT04863885 2025-12-17

Combination of Ipi/Nivo Plus Sacituzumab Govitecan in Metastatic Cisplatin Ineligible Urothelial Carcinoma Patients

46 enrolled

Phase 1/2 Not yet recruiting

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT07261592 2025-12-03

Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder Cancer

29 enrolled

Urinary Bladder Neoplasms

NCT04724018 2025-11-04

Sacituzumab Govitecan Plus EV in Metastatic UC

106 enrolled

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT06394570 2025-09-15

STAR-EV

19 enrolled

Urinary Bladder Neoplasms

NCT03185468 2025-09-08

Intervention of Bladder Cancer by CAR-T

20 enrolled

Urinary Bladder Neoplasms

NCT05057013 2025-08-11

A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

81 enrolled

Lethal Congenital Contracture Syndrome 2, Fibromatosis, Gingival, 2, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Prostatic Neoplasms, Castration-Resistant, Triple Negative Breast Neoplasms

NCT06364956 2025-08-11

Clinical Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

36 enrolled

Urinary Bladder Neoplasms

NCT05944237 2025-06-08

HTL0039732 in Participants With Advanced Solid Tumours

EndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

150 enrolled

Mesothelioma, Malignant, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Pheochromocytoma, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT06957561 2025-05-04

DIVON

Phase 1/2 Not yet recruiting

30 enrolled

Urinary Bladder Neoplasms

NCT04046094 2025-03-25

Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients

12 enrolled 9 charts

Urinary Bladder Neoplasms

NCT02365766 2025-03-18

Neoadjuvant Pembrolizumab in Combination With Gemcitabine Therapy in Cis-eligible/Ineligible UC Subjects

83 enrolled 14 charts

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT00583349 2025-02-17

Intravesicular Abraxane for Treatment-Refractory Bladder Cancer

46 enrolled 11 charts

Urinary Bladder Neoplasms

NCT04106115 2024-12-04

DURANCE

64 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT06341400 2024-12-04

RC48 Combined with Toripalimab As Neoadjuvant Therapy for Cisplatin Ineligible MIBC Patients

55 enrolled

Urinary Bladder Neoplasms

NCT04706598 2024-07-12

Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment

25 enrolled

Urinary Bladder Neoplasms

NCT03892642 2024-02-14

OU-SCC-ABC

18 enrolled 15 charts

Urinary Bladder Neoplasms

NCT05120622 2023-10-31

Rideau

Phase 1/2 Withdrawn

Urinary Bladder Neoplasms

NCT02371447 2023-04-13

VPM1002BC in Recurrent Non-muscle Invasive Bladder Cancer

39 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT02643303 2022-12-02

A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

BreastDermatologicGenitourinaryHead & NeckLymphoidSarcoma

58 enrolled 24 charts

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Kidney Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Testicular Neoplasms, Carcinoma, Merkel Cell, Lymphoma, T-Cell, Cutaneous

NCT00188695 2022-10-07

Combidex USPIO - Ultra-small Superparamagnetic Iron Oxide

61 enrolled

GenitourinaryGynecologic

Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Prostatic Neoplasms, Uterine Neoplasms

NCT03844256 2022-08-12

CRIMI

50 enrolled

Urinary Bladder Neoplasms

NCT04555343 2021-11-05

Intravesical Antifibrinolytic for Patients With Hematuria and Clot Retention

14 enrolled

Urinary Bladder Neoplasms, Hematuria, Prostatic Neoplasms, Urologic Diseases, Urinary Retention, Patient Satisfaction

NCT04922047 2021-06-11

TACBIN-01

Phase 1/2 Unknown

6 enrolled

Urinary Bladder Diseases, Urinary Bladder Neoplasms, Urogenital Neoplasms, Urologic Neoplasms

NCT03498196 2020-08-24

A Window of Opportunity Trial: Avelumab in Non-metastatic Muscle Invasive Bladder Cancer

Phase 1/2 Terminated

1 enrolled 10 charts

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT01342172 2019-04-23

Gemcitabine, Cisplatin, Plus Lenalidomide as First-line Therapy for Patients With Metastatic Urothelial Carcinoma

Phase 1/2 Terminated

9 enrolled 9 charts

Urinary Bladder Neoplasms, Neoplasm Metastasis

NCT00963404 2018-05-03

Image-Guided Tumorboost of Bladder Cancer

19 enrolled

Urinary Bladder Neoplasms

NCT01259063 2018-03-13

RAD001 and Intravesical Gemcitabine in BCG-Refractory Primary or Secondary Carcinoma In Situ of the Bladder

33 enrolled 11 charts

Urinary Bladder Neoplasms

NCT01090466 2018-02-06

Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium

15 enrolled

Urinary Bladder Neoplasms, Urethral Neoplasms

NCT01938573 2017-10-20

Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer

21 enrolled 4 charts

BreastGastrointestinalGenitourinaryThoracic

Urinary Bladder Neoplasms

NCT02886897 2016-09-01

A Study of Combinations of D-CIK Immunotherapy And Anti-PD-1 In Refractory Solid Tumors

Phase 1/2 Unknown

50 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Colorectal Neoplasms

NCT00588640 2016-08-10

Study of D-Methadone in Patients With Chronic Pain

BreastCNSGastrointestinalGenitourinaryGynecologicHead & Neck

10 enrolled 6 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Eye Neoplasms, Head and Neck Neoplasms, Otorhinolaryngologic Neoplasms, Pain, Pancreatic Neoplasms, Prostatic Neoplasms, Uterine Neoplasms, Central Nervous System Neoplasms

NCT00556621 2015-07-30

GEMCIRAV

14 enrolled

Urinary Bladder Neoplasms

NCT00003103 2013-07-03

Chemotherapy in Treating Patients With Solid Tumors

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

57 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Wilms Tumor, Ovarian Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00003105 2013-07-03

Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Bladder Cancer

30 enrolled

Urinary Bladder Neoplasms

NCT00322699 2012-10-26

Sequential Whole Bladder Photodynamic Therapy (WBPDT) in the Management of Superficial Bladder Cancer

22 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Photosensitivity Disorders

NCT01265940 2012-10-10

Pazopanib and Vinflunine in Urothelial Cancer of the Bladder

5 enrolled

Urinary Bladder Neoplasms

NCT00891748 2010-01-18

Safety Study on AdCD40L Gene Therapy for Bladder Cancer

12 enrolled

Urinary Bladder Neoplasms

NCT00818350 2009-01-07

Activity Study of Sunitinib In Metastatic Pretreated Urothelial Cancer

Phase 1/2 Unknown

25 enrolled

Urinary Bladder Neoplasms

NCT00696579 2008-06-12

Bacillus of Calmette and Guerin (BCG) Versus Gemcitabine For Intravesical Therapy In High Risk Superficial Bladder Cancer

64 enrolled

Urinary Bladder Neoplasms

NCT00393809 2008-01-07

Safety and Proof of Concept Study of Intravesical DTA-H19 in Patients With Superficial Bladder Cancer

18 enrolled