Clinical Trials

Phase 1/2 Active not recruiting

Uterine Cervical Neoplasms, Vaginal Neoplasms

NCT04287868 2026-04-13

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

51 enrolled 16 charts

GastrointestinalGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Oropharyngeal Neoplasms, Rectal Neoplasms

NCT04234113 2026-03-27

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Phase 1 Terminated

115 enrolled 43 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04300647 2026-03-12

SKYSCRAPER-04

172 enrolled 27 charts

Uterine Cervical Neoplasms

NCT04697628 2026-02-24

innovaTV 301

502 enrolled 18 charts 2 FDA

Uterine Cervical Neoplasms

NCT04221945 2026-02-20

KEYNOTE-A18

1,060 enrolled 30 charts 2 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Uterine Cervical Neoplasms

NCT03635567 2026-02-04

KEYNOTE-826

617 enrolled 29 charts 2 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Uterine Cervical Neoplasms

NCT02405221 2026-01-29

Safety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer

15 enrolled 16 charts

Phase NA Active not recruiting

Uterine Cervical Neoplasms

NCT03984695 2026-01-28

SHE-WOMEN

279 enrolled 17 charts

BreastGynecologic

Breast Neoplasms, Uterine Cervical Neoplasms, Contraception Behavior, Sexually Transmitted Diseases

NCT00980954 2025-12-31

Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy

236 enrolled 28 charts

Phase 2 Active not recruiting

Uterine Cervical Neoplasms

NCT04579380 2025-12-19

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

217 enrolled 19 charts

BreastGastrointestinalGenitourinaryGynecologicThoracic

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Urologic Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT02595879 2025-11-13

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Phase 1 Active not recruiting

21 enrolled 22 charts

Uterine Cervical Neoplasms

NCT03738228 2025-11-12

Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer

40 enrolled 17 charts

Uterine Cervical Neoplasms

NCT01676818 2025-11-06

Eribulin Mesylate in Treating Patients With Advanced or Recurrent Cervical Cancer

32 enrolled 17 charts

Uterine Cervical Neoplasms

NCT04363957 2025-10-14

Gynecologic Brachytherapy-Specific Educational Video

80 enrolled 7 charts

Uterine Cervical Neoplasms, Uterine Neoplasms

NCT04259762 2025-09-24

Enhancing Cancer Prevention and Control Pathways-Native Health Initiative

BreastGastrointestinalGynecologic

508 enrolled 8 charts

Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Colorectal Neoplasms

NCT04411849 2025-09-10

Multilevel HPV Self-Testing Intervention for the Increase of Cervical Cancer Screening Among Women in Appalachia

802 enrolled 5 charts

Phase 2 Active not recruiting

Uterine Cervical Neoplasms, Papillomavirus Infections

NCT02257528 2025-09-08

Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer

26 enrolled 12 charts

Uterine Cervical Neoplasms

NCT04646005 2025-09-08

Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy

113 enrolled 18 charts

Adenocarcinoma, Uterine Cervical Neoplasms, Neoplasm Metastasis, Recurrence

NCT00924027 2025-09-05

A Study of Patients Receiving High-Dose Rate Brachytherapy

GastrointestinalGenitourinaryGynecologic

43 enrolled 13 charts

Biliary Tract Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT03898167 2025-09-04

PRESTIS

2,474 enrolled 10 charts

Phase EARLY_PHASE1 Completed

Uterine Cervical Neoplasms, Papillomavirus Infections

NCT05105087 2025-08-22

Gynecological Sentinel Lymph Nodes CEUS

9 enrolled 10 charts

Uterine Cervical Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT06263582 2025-08-19

Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya

12 enrolled 18 charts

GynecologicLymphoid

Carcinoma in Situ, Uterine Cervical Dysplasia, Uterine Cervical Neoplasms, Lymphoma, Follicular

NCT03126110 2025-08-14

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

145 enrolled 47 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasm Metastasis, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04092257 2025-08-06

HPV-Based Screen-and-Treat Demonstration Project in Lilongwe

1,250 enrolled 12 charts

Uterine Cervical Neoplasms, HIV Infections, Papillomavirus Infections

NCT06048367 2025-08-03

CNSI-Fe(II)

BreastGastrointestinalGynecologicHead & NeckThoracic

19 enrolled 47 charts

Breast Neoplasms, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms

NCT00092534 2025-08-01

FUTURE II

12,167 enrolled 23 charts

Uterine Cervical Neoplasms, Condylomata Acuminata

NCT03104699 2025-07-30

A Study of AGEN2034 in Advanced Tumors and Cervical Cancer

211 enrolled 29 charts

Uterine Cervical Neoplasms

NCT03444376 2025-07-30

The Combination of GX-188E Vaccination and Pembrolizumab in Patients With HPV 16 and/or 18+ Advanced Cervical Cancer

65 enrolled 16 charts

Uterine Cervical Neoplasms

NCT05453006 2025-07-10

Isbaar

3,367 enrolled 8 charts

Uterine Cervical Diseases, Uterine Cervical Neoplasms, DNA Virus Infections, Infections, Papilloma, Tumor Virus Infections, Uterine Diseases, Virus Diseases, Papillomavirus Infections

NCT02635360 2025-07-03

Pembrolizumab and Chemoradiation Treatment for Advanced Cervical Cancer

94 enrolled 16 charts

Uterine Cervical Neoplasms

NCT04998318 2025-06-24

1:1 Comparison of the Pocket Colposcope in Kenya

434 enrolled 18 charts

Uterine Cervical Neoplasms, HIV Infections, Papillomavirus Infections

NCT01101451 2025-05-23

Radiation Therapy With or Without Chemotherapy in Patients With Stage I-IIA Cervical Cancer Who Previously Underwent Surgery

340 enrolled 13 charts

Uterine Cervical Neoplasms

NCT04483544 2025-04-29

Pembrolizumab and Olaparib in Cervical Cancer Patients

Phase 2 Terminated

8 enrolled 13 charts

Uterine Cervical Neoplasms

NCT04693234 2025-04-27

AdvanTIG-202: Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Previously Treated Recurrent or Metastatic Cervical Cancer

178 enrolled 26 charts

Uterine Cervical Neoplasms

NCT04514692 2025-04-23

Bone Marrow Sparing Image-Guided Radiation Therapy (RT) Incorporating Novel Use of GCSF and FDG-PET Imaging

Phase 1/2 Terminated

7 enrolled 9 charts

Uterine Cervical Neoplasms, Endometrial Neoplasms

NCT02487095 2025-04-13

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

EndocrineGynecologicThoracic

62 enrolled 29 charts

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Ovarian Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT03527264 2025-04-04

BrUOG 355: Nivolumab to Tailored Radiation Therapy With Concomitant Cisplatin in the Treatment of Patients With Cervical Cancer

Phase 2 Terminated

4 enrolled 11 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Uterine Cervical Neoplasms

NCT03829501 2025-04-02

A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies

Phase 1/2 Terminated

222 enrolled 49 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT04499521 2025-03-17

A Randomized Study to Compare a Hydrogel Packing System to Standard Packing During HDR Brachytherapy for Cervical Cancer

21 enrolled 8 charts

Uterine Cervical Neoplasms

NCT04492007 2025-02-03

PRISMS

GastrointestinalGenitourinaryGynecologic

46 enrolled 19 charts

Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT04508309 2025-01-30

Phase 3 Trial of a Bivalent Human Papilloma Virus (HPV) Vaccine (Cecolin®) in Young Girls

1,025 enrolled 32 charts

Uterine Cervical Neoplasms

NCT03483610 2025-01-24

Promoting Cervical Cancer Screening for Emergency Department Patients

95 enrolled 7 charts

Uterine Cervical Neoplasms

NCT01658930 2024-12-17

SHAPE

700 enrolled 12 charts

Uterine Cervical Neoplasms

NCT01554397 2024-11-29

Study With Intensity Modulated Radiation Therapy With Cisplatin to Treat Stage I-IVA Cervical Cancer

Phase 2/3 Completed

101 enrolled 13 charts

Carcinoma, Uterine Cervical Neoplasms

NCT05862844 2024-11-07

Promise Women Project

20 enrolled 8 charts

Uterine Cervical Neoplasms

NCT03551028 2024-11-04

HPV DNA Testing Through Mobile Mammography Unit

33 enrolled 5 charts

Uterine Cervical Neoplasms

NCT01600040 2024-10-29

Proton Beam Teletherapy for Post-Hysterectomy Cancers of the Uterus and Cervix

22 enrolled 6 charts

Uterine Cervical Neoplasms, Neoplasm Metastasis, Uterine Neoplasms

NCT05959564 2024-10-21

A Chatbot Intervention for Reducing HPV Vaccine Hesitancy