Clinical Trials Browser

Phase 1/2 × INDUSTRY × Uveal Melanoma × Clear all

Uveal Melanoma, Melanoma, Neoplasms, Ovarian Neoplasms, Recurrence

NCT03947385 2026-01-27

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

Phase 1/2 Recruiting

336 enrolled

DermatologicGastrointestinal

Uveal Melanoma, Melanoma, Colorectal Neoplasms

NCT04130516 2025-12-18

Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

Phase 1/2 Recruiting

200 enrolled

DermatologicGastrointestinalThoracic

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Melanoma, Stomach Neoplasms

NCT06940739 2025-12-03

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

Phase 1/2 Recruiting

42 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT07136181 2025-11-28

NBM-BMX-UM

Phase 1/2 Recruiting

36 enrolled

Dermatologic

Uveal Melanoma, Eye Neoplasms, Neoplasm Metastasis, Recurrence

NCT06784648 2025-11-19

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

Phase 1/2 Active not recruiting

35 enrolled

Dermatologic

Uveal Melanoma, Melanoma, Neoplasm Metastasis

NCT03611868 2025-08-07

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Phase 1/2 Active not recruiting

230 enrolled

DermatologicSarcoma

Uveal Melanoma, Melanoma, Neurofibrosarcoma

NCT05415072 2025-07-20

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

Phase 1/2 Active not recruiting

66 enrolled

Dermatologic

Uveal Melanoma, Eye Neoplasms, Melanoma, Neoplasms

NCT03052127 2024-02-01

Study in Subjects With Small Primary Choroidal Melanoma

Phase 1/2 Completed

57 enrolled 26 charts

Dermatologic

Uveal Melanoma, Eye Neoplasms

NCT02743611 2023-10-05

Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma

Phase 1/2 Terminated

4 enrolled 9 charts

DermatologicMyeloidOther hematologic neoplasm

Uveal Melanoma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT02570308 2023-03-21

A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma

Phase 1/2 Completed

146 enrolled 26 charts

Dermatologic

Uveal Melanoma, Melanoma

NCT01801358 2020-09-16

A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma

Phase 1/2 Terminated

38 enrolled 31 charts

Dermatologic

Uveal Melanoma, Melanoma

Clinical Trials

ACTengine

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

NBM-BMX-UM

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

Study in Subjects With Small Primary Choroidal Melanoma

Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma

A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma

A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma