Clinical Trials

36 enrolled

Uveal Melanoma, Melanoma

NCT03947385 2026-01-27

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

DermatologicGastrointestinal

336 enrolled

Uveal Melanoma, Melanoma, Colorectal Neoplasms

NCT04130516 2025-12-18

Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

DermatologicGastrointestinalThoracic

200 enrolled

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Melanoma, Stomach Neoplasms

NCT06940739 2025-12-03

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

42 enrolled

Uveal Melanoma, Melanoma

NCT06626516 2025-11-28

Tebentafusp-tebn With LDT in Metastatic UM

109 enrolled

Uveal Melanoma, Melanoma

NCT07136181 2025-11-28

NBM-BMX-UM

36 enrolled

Uveal Melanoma, Eye Neoplasms, Neoplasm Metastasis, Recurrence

NCT06784648 2025-11-19

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

35 enrolled

Phase 1/2 Enrolling by invitation

Uveal Melanoma, Melanoma, Neoplasm Metastasis

NCT05893654 2025-09-15

MELCOM

10 enrolled

Uveal Melanoma, Melanoma

NCT04283890 2025-09-09

CHOPIN

83 enrolled

Uveal Melanoma, Neoplasm Metastasis

NCT03611868 2025-08-07

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

230 enrolled

DermatologicSarcoma

Uveal Melanoma, Melanoma, Neurofibrosarcoma

NCT05415072 2025-07-20

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

66 enrolled

Uveal Melanoma, Eye Neoplasms, Melanoma, Neoplasms

NCT07063875 2025-07-14

SILVER

8 enrolled

Uveal Melanoma

NCT04364230 2024-07-16

Mel66

22 enrolled

Uveal Melanoma, Melanoma, Nevus

NCT03052127 2024-02-01

Study in Subjects With Small Primary Choroidal Melanoma

57 enrolled 26 charts

Uveal Melanoma, Eye Neoplasms

NCT04729543 2023-12-04

MC2TCR

20 enrolled

DermatologicHead & Neck

Uveal Melanoma, Head and Neck Neoplasms, Melanoma

NCT04589832 2023-11-22

Study of PAC-1 and Entrectinib for Patients With Metastatic Uveal Melanoma

6 enrolled 9 charts

Uveal Melanoma

NCT02743611 2023-10-05

Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma

DermatologicMyeloidOther hematologic neoplasm

4 enrolled 9 charts

Uveal Melanoma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05677373 2023-08-18

Testing the Safety and Effectiveness of Combining Two Drugs, PLX2853 and Trametinib in the Treatment of Advanced Uveal Melanoma

Phase 1/2 Withdrawn

Uveal Melanoma

NCT02570308 2023-03-21

A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma

146 enrolled 26 charts

Uveal Melanoma, Melanoma

NCT05047276 2021-09-17

PULSE-UM

16 enrolled

Uveal Melanoma, Neoplasm Metastasis

NCT02913417 2021-04-19

Yttrium90, Ipilimumab, & Nivolumab for Uveal Melanoma With Liver Metastases

26 enrolled

Uveal Melanoma

NCT01801358 2020-09-16

A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma

38 enrolled 31 charts

Uveal Melanoma, Melanoma

NCT00929019 2018-12-07

Messenger Ribonucleic Acid (mRNA) Transfected Dendritic Cell Vaccination in High Risk Uveal Melanoma Patients

23 enrolled

Uveal Melanoma

NCT02654821 2018-11-02

TCR

12 enrolled

Uveal Melanoma, Melanoma

NCT03326258 2018-07-18

Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery

Phase 1/2 Withdrawn

BreastDermatologic

Uveal Melanoma, Breast Neoplasms, Melanoma, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT00089219 2014-11-20

Vaccine Therapy in Treating Patients With Stage IIIB, Stage IIIC, or Stage IV Melanoma

39 enrolled

Uveal Melanoma, Melanoma

NCT00058279 2013-06-20

Monoclonal Antibody Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma

Uveal Melanoma, Melanoma

NCT00005815 2013-06-19

Temozolomide and Thalidomide in Treating Patients With Stage III or Stage IV Melanoma

Uveal Melanoma, Melanoma

NCT00111046 2005-11-10

Pain Relief - Tramadol Versus Ibuprofen

40 enrolled