Clinical Trials Browser

Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Meningeal Neoplasms, Nevus

NCT05628883 2026-04-02

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

Phase 1 Completed

17 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT07501117 2026-03-30

Neoadjuvant Immunotherapy for Patients With High-risk Eye Melanoma

Phase 1 Not yet recruiting

15 enrolled

Dermatologic

Uveal Melanoma

NCT04119024 2026-03-17

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Phase 1 Recruiting

18 enrolled

BreastCNSDermatologicEndocrineHead & NeckNETThoracic

Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Adenoma, Islet Cell, Melanoma, Neoplasm Metastasis, Paraganglioma, Pheochromocytoma, Thyroid Neoplasms, Adrenocortical Carcinoma, Neuroendocrine Tumors

NCT01046487 2026-03-13

PALANGI3

Phase 1 Completed

26 enrolled

DermatologicGastrointestinalSarcoma

Uveal Melanoma, Chordoma, Carcinoma, Adenoid Cystic, Neoplasms, Desmoid Tumors, Dermatofibrosarcoma, Gastrointestinal Stromal Tumors

NCT02858869 2026-03-09

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

Phase 1 Completed

25 enrolled 14 charts

CNSDermatologicThoracic

Uveal Melanoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05607095 2026-02-04

A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma

Phase 1 Recruiting

30 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT03865212 2026-01-28

Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma

Phase 1 Terminated

12 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT05075993 2025-12-26

Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors

Phase 1 Active not recruiting

352 enrolled

DermatologicGastrointestinalGynecologicSarcoma

Uveal Melanoma, Carcinoma, Hepatocellular, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms

NCT04082962 2025-12-17

Dexamethasone Implant for Retinal Detachment in Uveal Melanoma

Phase 1 Completed

10 enrolled

Dermatologic

Uveal Melanoma

NCT07203391 2025-10-02

TRIUMPH

Phase 1 Recruiting

8 enrolled

Dermatologic

Uveal Melanoma, Neoplasm Metastasis

NCT05004025 2025-08-15

Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma

Phase 1 Completed

10 enrolled

Dermatologic

Uveal Melanoma

NCT05341349 2025-07-30

Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases

Phase 1 Active not recruiting

1 enrolled

CNSDermatologic

Uveal Melanoma, Brain Neoplasms, Melanoma

NCT03635632 2025-07-25

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Phase 1 Active not recruiting

94 enrolled

BreastCNSDermatologicSarcoma

Uveal Melanoma, Breast Neoplasms, Phyllodes Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT03922880 2025-05-15

Study of Immunotherapy Plus ADI-PEG 20 for the Treatment of Advanced Uveal Melanoma

Phase 1 Completed

9 enrolled

Dermatologic

Uveal Melanoma

NCT05169957 2024-11-05

Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I)

Phase 1 Completed

2 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT03068624 2024-01-25

Autologous CD8+ SLC45A2-Specific T Lymphocytes With Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma

Phase 1 Unknown

34 enrolled

Dermatologic

Uveal Melanoma

NCT02768766 2023-08-31

Intermittent Selumetinib for Uveal Melanoma

Phase 1 Completed

42 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT02273219 2023-08-15

Trial of AEB071 in Combination With BYL719 in Patients With Melanoma

Phase 1 Completed

30 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT01005472 2020-08-03

Temozolomide and Sunitinib Malate in Treating Patients With Stage III or Stage IV Malignant Melanoma

Phase 1 Completed

16 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT01893099 2018-04-23

Sorafenib and Radioembolization With Sir-Spheres® for the Treatment of Metastatic Ocular Melanoma

Phase 1 Completed

11 enrolled

Dermatologic

Uveal Melanoma

NCT00471471 2017-06-22

Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Phase 1 Completed

22 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT00398073 2017-03-16

Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma

Phase 1 Completed

35 enrolled 9 charts

Dermatologic

Uveal Melanoma, Melanoma

NCT00705640 2016-12-16

Mel48

Phase 1 Completed

45 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT00765921 2016-12-02

Ranibizumab in Combination With Proton Beam Irradiation for Choroidal Melanoma

Phase 1 Completed

40 enrolled

Dermatologic

Uveal Melanoma, Macular Edema, Glaucoma, Neovascular

NCT00002947 2014-07-02

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Phase 1 Terminated

35 enrolled

CNSDermatologicEndocrineGenitourinaryHead & NeckThoracic

Uveal Melanoma, Carcinoma, Renal Cell, Vipoma, Glucagonoma, Head and Neck Neoplasms, Insulinoma, Adenoma, Islet Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Pheochromocytoma, Somatostatinoma, Carcinoma, Merkel Cell, Gastrinoma, Central Nervous System Neoplasms, Carcinoma, Islet Cell, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT00005841 2014-05-22

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

Phase 1 Terminated

15 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT00025181 2014-05-22

Monoclonal Antibody and Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Has Been Removed During Surgery

Phase 1 Completed

19 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT00313508 2014-02-21

Dendritic Cell Vaccination During Lymphoid Reconstruction

Phase 1 Completed

18 enrolled

Dermatologic

Uveal Melanoma, Melanoma

NCT00003022 2013-07-03

Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer

Phase 1 Completed

CNSDermatologicOther solid neoplasmSarcomaThoracic

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neuroblastoma, Oligodendroglioma, Retinoblastoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Gliosarcoma, Optic Nerve Glioma, Small Cell Lung Carcinoma

NCT00750399 2012-04-26

Effect of Intravitreal Ranibizumab on Radiation Retinopathy Following Plaque Brachytherapy for Choroidal Melanoma

Phase 1 Completed

10 enrolled

Dermatologic

Uveal Melanoma, Melanoma, Retinal Diseases

Clinical Trials

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

Neoadjuvant Immunotherapy for Patients With High-risk Eye Melanoma

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

PALANGI3

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma

Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma

Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors

Dexamethasone Implant for Retinal Detachment in Uveal Melanoma

TRIUMPH

Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma

Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Study of Immunotherapy Plus ADI-PEG 20 for the Treatment of Advanced Uveal Melanoma

Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I)

Autologous CD8+ SLC45A2-Specific T Lymphocytes With Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma

Intermittent Selumetinib for Uveal Melanoma

Trial of AEB071 in Combination With BYL719 in Patients With Melanoma

Temozolomide and Sunitinib Malate in Treating Patients With Stage III or Stage IV Malignant Melanoma

Sorafenib and Radioembolization With Sir-Spheres® for the Treatment of Metastatic Ocular Melanoma

Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma

Mel48

Ranibizumab in Combination With Proton Beam Irradiation for Choroidal Melanoma

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

Monoclonal Antibody and Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Has Been Removed During Surgery

Dendritic Cell Vaccination During Lymphoid Reconstruction

Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer

Effect of Intravitreal Ranibizumab on Radiation Retinopathy Following Plaque Brachytherapy for Choroidal Melanoma