Clinical Trials Browser

Phase 1 × Completed × Vaccinia × Clear all

Neoplasms, Vaccinia

NCT03954067 2025-04-22

A Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors

Phase 1 Completed

72 enrolled

Neoplasm Metastasis, Vaccinia

NCT05376527 2025-03-24

Open Multi-cohort Study of the First Phase of Safety of a Drug Based on Double Recombinant Vaccinia Virus VV-GMCSF-Lact

Phase 1 Completed

34 enrolled

Breast

Breast Neoplasms, Vaccinia

NCT01169584 2016-01-21

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients

Phase 1 Completed

6 enrolled

CNSGenitourinaryLymphoidSarcoma

Lymphoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Vaccinia, Neurofibrosarcoma

NCT01380600 2016-01-08

Safety Study of Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma

Phase 1 Completed

15 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Vaccinia, Colorectal Neoplasms

NCT00574977 2015-12-28

Safety Study of Modified Vaccinia Virus to Cancer

Phase 1 Completed

26 enrolled

BreastDermatologicGastrointestinal

Adenocarcinoma, Breast Neoplasms, Liver Neoplasms, Melanoma, Neoplasms, Vaccinia, Virus Diseases, Colorectal Neoplasms, Neoplasms, Squamous Cell

NCT00625456 2015-12-03

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors

Phase 1 Completed

23 enrolled

DermatologicGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Vaccinia

NCT01584284 2015-08-25

Safety Study of Attenuated Vaccinia Virus (GL-ONC1)With Combination Therapy in Head & Neck Cancer

Phase 1 Completed

19 enrolled

Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Vaccinia

NCT00629759 2013-01-04

A Study of Recombinant Vaccinia Virus to Evaluate the Safety and Efficacy of a Transdermal Injection Within the Tumor of Patients With Primary or Metastatic Hepatic Carcinoma

Phase 1 Completed

14 enrolled

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms, Vaccinia

Clinical Trials

Safety Study of GL-ONC1, an Oncolytic Virus, in Patients With Advanced Solid Tumors

A Study of an Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors

Open Multi-cohort Study of the First Phase of Safety of a Drug Based on Double Recombinant Vaccinia Virus VV-GMCSF-Lact

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients

Safety Study of Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma

Safety Study of Modified Vaccinia Virus to Cancer

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors

Safety Study of Attenuated Vaccinia Virus (GL-ONC1)With Combination Therapy in Head & Neck Cancer

A Study of Recombinant Vaccinia Virus to Evaluate the Safety and Efficacy of a Transdermal Injection Within the Tumor of Patients With Primary or Metastatic Hepatic Carcinoma