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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other hematologic neoplasm 1Lymphoid 1Gynecologic 1Genitourinary 1Dermatologic 1Breast 1

Conditions

Polycystic Ovary Syndrome 149Breast Neoplasms 38Prostatic Neoplasms 31Insulin Resistance 30Obesity 23Endometrial Neoplasms 15Neoplasms 14Infertility 14Colorectal Neoplasms 13Pancreatic Neoplasms 12Carcinoma, Non-Small-Cell Lung 12Anovulation 10Lung Neoplasms 9Neoplasm Metastasis 8Hyperandrogenism 8Glioblastoma 8Diabetes Mellitus 8Squamous Cell Carcinoma of Head and Neck 7Metabolic Syndrome 7Melanoma 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Ovarian Neoplasms 5Lymphoma, Large B-Cell, Diffuse 5Head and Neck Neoplasms 5Brain Neoplasms 5Adenocarcinoma 5Weight Loss 4Uterine Cervical Neoplasms 4Urinary Bladder Neoplasms 4Rectal Neoplasms 4

Interventions

Rituximab 99Cyclophosphamide 63fludarabine phosphate 54Peripheral Blood Stem Cell Transplantation 52Mycophenolic Acid 33Bortezomib 33Whole-Body Irradiation 32ibrutinib 29Dexamethasone 27Tacrolimus 25Cyclosporine 25Etoposide 22Busulfan 22Melphalan 20Filgrastim 20Methotrexate 18Lenalidomide 18Antilymphocyte Serum 18Radiotherapy 16zanubrutinib 14Bendamustine Hydrochloride 14Sirolimus 13Calcium Dobesilate 11Everolimus 10venetoclax 9ibritumomab tiuxetan 9Prednisone 9Cyclosporins 9idelalisib 8Indium 8

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Waldenstrom Macroglobulinemia × Metformin × Clear all
NCT00659568 2013-05-30

Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma

National Cancer Institute (NCI)

Phase 1 Completed
28 enrolled
BreastDermatologicGenitourinaryGynecologicLymphoidOther hematologic neoplasmThoracic

Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Renal Cell, Hodgkin Disease, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Small Cell Lung Carcinoma

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