Announcements Trials
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Phase

Phase 2 4

Status

Recruiting 4Active not recruiting 3Completed 2

Sponsor Class

OTHER 2NIH 1INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Lymphoid 4

Conditions

Leukemia, Myeloid, Acute 124Leukemia, Lymphocytic, Chronic, B-Cell 30Myelodysplastic Syndromes 27Leukemia 21Precursor Cell Lymphoblastic Leukemia-Lymphoma 18Recurrence 17Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 10Lymphoma 9Leukemia, Biphenotypic, Acute 8Hematologic Neoplasms 8Leukemia, Myelomonocytic, Chronic 7Neoplasm, Residual 6Multiple Myeloma 6Lymphoma, Mantle-Cell 6Burkitt Lymphoma 6Neoplasms 5Waldenstrom Macroglobulinemia 4Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4Myeloproliferative Disorders 4Lymphoma, Non-Hodgkin 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Myeloid 4Leukemia, Monocytic, Acute 3GATA2 Deficiency 3Sarcoma, Myeloid 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Immunoglobulin Light-chain Amyloidosis 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Anemia, Refractory, with Excess of Blasts 2

Interventions

Rituximab 7zanubrutinib 6venetoclax 4ibrutinib 3Dexamethasone 3Specimen Handling 2Magnetic Resonance Spectroscopy 2Cyclophosphamide 2Blood Specimen Collection 2Biopsy 2Bendamustine Hydrochloride 2pirtobrutinib 1obinutuzumab 1Positron-Emission Tomography 1Lenalidomide 1Exercise 1Diet 1CT-P10 1Bortezomib 1ARQ531 111-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Recruiting × Waldenstrom Macroglobulinemia × venetoclax × Clear all
NCT04840602 2026-06-05

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

National Cancer Institute (NCI)

Phase 2 Recruiting
92 enrolled
Lymphoid

Waldenstrom Macroglobulinemia, Lymphoma, B-Cell, Marginal Zone

NCT07231952 2026-06-03

A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

Memorial Sloan Kettering Cancer Center

Phase 2 Recruiting
40 enrolled
Lymphoid

Waldenstrom Macroglobulinemia, Lymphoma, B-Cell, Marginal Zone

NCT07387471 2026-05-29

Study to Assess Change in Disease Activity of Oral Venetoclax in Adult Participants With Recurring Relapsed or Refractory (R/R) Waldenström Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

AbbVie

Phase 2 Recruiting
14 enrolled
Lymphoid

Waldenstrom Macroglobulinemia, Neoplasms, Lymphoma, B-Cell, Marginal Zone

NCT05099471 2026-05-05

VIWA-1

University of Ulm

Phase 2 Recruiting
80 enrolled
Lymphoid

Lymphoma, Waldenstrom Macroglobulinemia, Neoplasms

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