Announcements Trials
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Phase

Phase NA 38Phase 2 11Phase 3 6Phase 1 6Phase 4 4Phase EARLY_PHASE1 2Phase 2/3 1Phase 1/2 1

Status

Completed 3Active not recruiting 2Unknown 1

Sponsor Class

OTHER 4NIH 1INDUSTRY 1

Study Type

Interventional 6

Sponsor

Cancer Type

Head & Neck 6

Conditions

Neoplasms 2009Carcinoma, Non-Small-Cell Lung 1222Breast Neoplasms 1214Leukemia, Myeloid, Acute 965Neoplasm Metastasis 900Melanoma 777Colorectal Neoplasms 749Lymphoma 725Multiple Myeloma 723Ovarian Neoplasms 673Pancreatic Neoplasms 664Prostatic Neoplasms 657Lymphoma, Non-Hodgkin 657Recurrence 636Precursor Cell Lymphoblastic Leukemia-Lymphoma 583Lung Neoplasms 559Leukemia, Lymphocytic, Chronic, B-Cell 555Glioblastoma 527Leukemia 485Lymphoma, Large B-Cell, Diffuse 440Lymphoma, Follicular 418Brain Neoplasms 413Squamous Cell Carcinoma of Head and Neck 388Stomach Neoplasms 386Carcinoma, Renal Cell 384Myelodysplastic Syndromes 381Carcinoma, Hepatocellular 367Advanced Solid Tumors 356Lymphoma, Mantle-Cell 345Glioma 342

Interventions

Mouthwashes 1Genetic Engineering 1Chewing Gum 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 1 × Xerostomia × Clear all
NCT07431645 2026-03-03

Pilot Study of Radiation-Induced Xerostomia Treatment With Allogeneic Mesenchymal Stromal Stem Cells

Institute of Oncology Ljubljana

Phase 1 Completed
10 enrolled
Head & Neck

Head and Neck Neoplasms, Xerostomia

NCT05820711 2026-02-09

Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy

University of Wisconsin, Madison

Phase 1 Active not recruiting
23 enrolled
Head & Neck

Head and Neck Neoplasms, Xerostomia

NCT02446249 2025-09-25

Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction

MeiraGTx UK II Ltd

Phase 1 Active not recruiting
17 enrolled
Head & Neck

Head and Neck Neoplasms, Xerostomia

NCT00595933 2022-09-07

Comparing Over-the-counter Dry Mouth Remedies After Radiation

University of Oklahoma

Phase 1 Completed
28 enrolled
Head & Neck

Head and Neck Neoplasms, Xerostomia

NCT03874572 2021-01-29

MESRIX-SAFETY

Rigshospitalet, Denmark

Phase 1 Unknown
10 enrolled
Head & Neck

Oropharyngeal Neoplasms, Salivary Gland Diseases, Xerostomia

NCT00372320 2018-09-11

Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
17 enrolled
Head & Neck

Adenoviridae Infections, Head and Neck Neoplasms, Xerostomia

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