Clinical Trials

Phase 1 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms, Oropharyngeal Neoplasms, Xerostomia

NCT05820711 2026-02-09

Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy

23 enrolled

Head and Neck Neoplasms, Xerostomia

NCT05106608 2026-01-05

LAXER

60 enrolled

Phase 2 Not yet recruiting

Head and Neck Neoplasms, Neoplasms, Xerostomia

NCT07290946 2025-12-18

MESRIX-more

100 enrolled

Phase 1 Active not recruiting

Head and Neck Neoplasms, Sjogren's Syndrome, Xerostomia

NCT05859711 2025-09-29

Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer Patients

Phase 4 Completed

90 enrolled

Xerostomia

NCT02446249 2025-09-25

Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction

17 enrolled

Phase EARLY_PHASE1 Completed

Head and Neck Neoplasms, Xerostomia

NCT05403125 2025-09-17

SDF Application in Oral Cancer Patients to Prevent Dental Caries

56 enrolled

Dental Caries, Pharyngeal Neoplasms, Xerostomia

NCT04805528 2025-09-11

Study of Non-invasive Acupuncture-like Transcutaneous Electrical Nerve Stimulation (Altens) to Help Alleviate Xerostomia After Radiation Therapy for Cancers of the Head and Neck

75 enrolled

Head and Neck Neoplasms, Xerostomia

NCT06276946 2025-09-05

Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia

Phase NA Withdrawn

Head and Neck Neoplasms, Oropharyngeal Neoplasms, Xerostomia

NCT03552965 2025-09-02

Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC

23 enrolled 21 charts

Squamous Cell Carcinoma of Head and Neck, Xerostomia

NCT06465628 2025-05-28

Acupressure on Xerostomia in Head and Neck Cancer Patients

126 enrolled

Head and Neck Neoplasms, Xerostomia

NCT05882890 2025-05-14

Does Craniosacraltherapy Combined With Exercises That Focuses om Respiration and Posture in the Upper Body Have an Effect on Xerostomia and Other Late Sequelae on People Who Has Been Suffering From Cancer in Mouth and Throat?

11 enrolled 12 charts

Xerostomia, Respiratory Aspiration

NCT06122636 2025-04-03

HNC

62 enrolled

Dental Plaque, Head and Neck Neoplasms, Periodontal Diseases, Stomatitis, Xerostomia, Dysbiosis

NCT04222478 2025-02-12

AURICULOXERO

Phase NA Not yet recruiting

68 enrolled

Xerostomia

NCT05872464 2024-06-24

Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia

52 enrolled

Xerostomia

NCT06413550 2024-05-14

The Efficacy of Hibiscus Sabdariffa in Xerostomia

40 enrolled

Xerostomia

NCT04608773 2024-02-01

Blinded Dry Mouth Spray Crossover Study

129 enrolled 12 charts

Head and Neck Neoplasms, Xerostomia

NCT04717765 2023-11-29

Photobiomodulation in Oral Lesions Resulting From Anti-neoplastic Prevention

60 enrolled

Head and Neck Neoplasms, Mouth Neoplasms, Osteoradionecrosis, Stomatitis, Xerostomia, Bisphosphonate-Associated Osteonecrosis of the Jaw

NCT05614843 2023-10-10

Photobiomodulation Therapy in Patients With Head and Neck Cancer Post-Radiotherapy

32 enrolled

Head and Neck Neoplasms, Neoplasms, Xerostomia

NCT02990468 2023-03-15

BMX-HN

Phase 1/2 Completed

29 enrolled 14 charts

Head & NeckOther

Head and Neck Neoplasms, Xerostomia, Mucositis

NCT05242991 2023-03-09

Effectiveness of Photobiomodulation Protocols in Radiation-induced Oral Side Effects in H&N Cancer Patients

132 enrolled

Head & NeckOther

Head and Neck Neoplasms, Taste Disorders, Trismus, Xerostomia, Mucositis

NCT05759975 2023-03-08

Effectiveness of Extraoral Photobiomodulation in Management of Oral Adverse Effects in Patients Undergoing HSCT

Other hematologic neoplasm

42 enrolled

Stomatitis, Xerostomia, Hematologic Neoplasms

NCT02513238 2022-12-28

MESRIX

Phase 2 Completed

30 enrolled 5 charts

Xerostomia

NCT00595933 2022-09-07

Comparing Over-the-counter Dry Mouth Remedies After Radiation

Phase 1 Completed

28 enrolled

Head and Neck Neoplasms, Xerostomia

NCT02292368 2022-09-01

Neurological Effects of Acupuncture to Prevent Radiation-induced Xerostomia

30 enrolled

Head and Neck Neoplasms, Nasopharyngeal Neoplasms, Xerostomia

NCT02474095 2022-07-25

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation in Treating Radiation-Induced Xerostomia in Patients With Head and Neck Cancer

30 enrolled

Xerostomia

NCT04880148 2021-12-09

HONEY

200 enrolled

Head and Neck Neoplasms, Radiation Injuries, Stomatitis, Xerostomia

NCT02941276 2021-11-03

LEONIDAS-2

84 enrolled

Head and Neck Neoplasms, Xerostomia

NCT04738227 2021-07-30

Effect of Low-level Laser Therapy on Salivary Flow, pH and Quality of Life in Irradiated Oropharyngeal Cancer Patients

34 enrolled

Xerostomia

NCT01874587 2021-07-27

ARTIX

Phase 3 Completed

132 enrolled

Oropharyngeal Neoplasms, Xerostomia

NCT00430378 2021-06-10

Acupuncture for Prevention of Radiation-Induced Xerostomia

100 enrolled

Nasopharyngeal Neoplasms, Xerostomia

NCT04007081 2021-03-24

Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia

12 enrolled

Head and Neck Neoplasms, Xerostomia

NCT03874572 2021-01-29

MESRIX-SAFETY

Phase 1 Unknown

10 enrolled

Oropharyngeal Neoplasms, Salivary Gland Diseases, Xerostomia

NCT04700475 2021-01-08

Effect of Low Level Laser Therapy on Prevention of Radiotherapy Induced Xerostomia in Cancer Patients.

60 enrolled

Head and Neck Neoplasms, Xerostomia

NCT00862550 2020-12-30

Xerostomia Pilot Fudan: Acupuncture for Prevention of Radiation-Induced Xerostomia

23 enrolled

Nasopharyngeal Carcinoma, Head and Neck Neoplasms, Xerostomia

NCT03151889 2020-08-12

TENS_HIR

67 enrolled

Head and Neck Neoplasms, Xerostomia

NCT04491435 2020-07-29

Saliva Substitute Mouthwash in NPC Survivors With Xerostomia: A Randomized Controlled Trial

94 enrolled

Phase EARLY_PHASE1 Terminated

Nasopharyngeal Neoplasms, Xerostomia

NCT03601962 2020-01-27

Effects of Aqualief® in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer

Phase NA Terminated

100 enrolled

Xerostomia

NCT03578432 2019-12-02

Everolimus in Restoring Salivary Gland Function in Participants With Locally Advanced Head and Neck Cancer Treated With Radiation Therapy

2 enrolled

Head and Neck Neoplasms, Mouth Neoplasms, Xerostomia

NCT00656513 2019-11-19

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Phase 2/3 Completed

196 enrolled 13 charts

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Xerostomia

NCT03302676 2019-03-14

The Use of Chewing Gum for Xerostomia and Hyposalivation After Radiotherapy for Oral and Oropharyngeal Tumors

109 enrolled

Head and Neck Neoplasms, Xerostomia

NCT03035825 2019-02-08

Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients

73 enrolled

Head and Neck Neoplasms, Xerostomia

NCT00068237 2019-02-05

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

Phase 2 Completed

49 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Xerostomia

NCT01833650 2018-09-25

The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer

120 enrolled

Sialadenitis, Thyroid Neoplasms, Xerostomia

NCT00372320 2018-09-11

Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer

Phase 1 Completed

17 enrolled