Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 4 1Phase 3 1Phase 1 1

Status

Completed 4Terminated 1Active not recruiting 1

Sponsor Class

INDUSTRY 4OTHER 1NIH 1

Study Type

Interventional 5Observational 1

Sponsor

Cancer Type

Thoracic 4Tumor-Agnostic 1CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 3Neuroblastoma 1Lung Neoplasms 1Carcinoma 1

Interventions

pembrolizumab 308Nivolumab 160Carboplatin 158Cisplatin 140Cyclophosphamide 137Paclitaxel 128Magnetic Resonance Spectroscopy 98Specimen Handling 95Radiotherapy 92Dexamethasone 88Gemcitabine 88Ipilimumab 83Biopsy 81Docetaxel 78Doxorubicin 76Rituximab 70Etoposide 69Lenalidomide 61durvalumab 61Radiation 60Prednisone 59atezolizumab 59Taxes 58Pemetrexed 57fludarabine 55Bevacizumab 54Cytarabine 52Vincristine 52olaparib 52Fluorouracil 48

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Has results × lorlatinib × 1 year × Clear all
NCT03737994 2026-04-23

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 2 Terminated
10 enrolled 17 charts
Thoracic

Lung Neoplasms

NCT06282991 2026-03-10

A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer Which Could Not Be Controlled

Pfizer

Completed
73 enrolled 12 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03052608 2025-11-25

A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC

Pfizer

Phase 3 Active not recruiting
296 enrolled 28 charts 1 FDA
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03909971 2025-11-05

A Study of Lorlatinib in ALK Inhibitor-Treated ALK-Positive NSCLC in China

Pfizer

Phase 2 Completed
109 enrolled 33 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03107988 2025-09-15

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

New Approaches to Neuroblastoma Therapy Consortium

Phase 1 Completed
65 enrolled 38 charts
CNS

Neuroblastoma

NCT04362072 2025-06-11

Study of Lorlatinib In People With ALK-positive Non-small Cell Lung Cancer

Pfizer

Phase 4 Completed
71 enrolled 26 charts
Tumor-Agnostic

Carcinoma

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