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Phase

Phase 1 2Phase 2 1Phase 1/2 1

Status

Completed 2Terminated 1Active not recruiting 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4Other solid neoplasm 2

Conditions

Carcinoma, Non-Small-Cell Lung 3Pleural Diseases 2Small Cell Lung Carcinoma 1Mesothelioma, Malignant 1Lung Neoplasms 1Epitheliod Malignant Pleural Mesothelioma 1

Interventions

pembrolizumab 603Cyclophosphamide 545Magnetic Resonance Spectroscopy 527Radiotherapy 513Specimen Handling 505Nivolumab 411Cisplatin 381Carboplatin 369Biopsy 305Blood Specimen Collection 304Radiosurgery 290Paclitaxel 281Gemcitabine 271Surveys and Questionnaires 269Standard of Care 267fludarabine 263Drug Therapy 263Dexamethasone 263Bevacizumab 252venetoclax 251Oxaliplatin 209Capecitabine 199Rituximab 198Radiation 191Ipilimumab 188Fluorouracil 188durvalumab 185Doxorubicin 178Etoposide 177atezolizumab 172

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × Dihematoporphyrin Ether × 1 year × Clear all
NCT03735095 2026-05-14

Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer

Roswell Park Cancer Institute

Phase 1/2 Completed
19 enrolled 10 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Small Cell Lung Carcinoma

NCT03678350 2026-03-27

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Roswell Park Cancer Institute

Phase 1 Completed
9 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT04836429 2026-02-04

Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease

Roswell Park Cancer Institute

Phase 1 Terminated
5 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT02153229 2025-12-26

MPM-PDT

Abramson Cancer Center at Penn Medicine

Phase 2 Active not recruiting
52 enrolled
Other solid neoplasmThoracic

Epitheliod Malignant Pleural Mesothelioma

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