Clinical Trials

7 enrolled

Colorectal Neoplasms

NCT04523857 2026-05-26

ABBY

Phase 2 Recruiting

44 enrolled

Phase EARLY_PHASE1 Active not recruiting

Breast Neoplasms

NCT05365893 2026-05-22

PHL Treatment in Pancreatic Cancer

20 enrolled

Phase 1/2 Active not recruiting

Pancreatic Ductal Adenocarcinoma

NCT03598595 2026-05-14

Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma

31 enrolled

Sarcoma

Osteosarcoma

NCT03825289 2026-05-14

THREAD

Phase 1 Terminated

25 enrolled

GenitourinaryOther solid neoplasm

Pancreatic Neoplasms

NCT05036226 2026-05-13

COAST

Phase 1/2 Recruiting

76 enrolled

Prostate Cancer Recurrent

NCT04464759 2026-05-11

LIMIT

Phase 1/2 Recruiting

94 enrolled

Dermatologic

Melanoma

NCT05842174 2026-04-16

TAQE

Phase 1/2 Recruiting

93 enrolled

Phase 1 Active not recruiting

Carcinoma, Hepatocellular

NCT01480154 2026-04-13

Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer

62 enrolled

DermatologicGenitourinary

Carcinoma, Renal Cell, Melanoma, Prostatic Neoplasms

NCT05518110 2026-04-13

PaTcH

Phase 2 Terminated

20 enrolled

Pancreatic Neoplasms

NCT04841148 2026-04-09

PALAVY

Phase 2 Recruiting

96 enrolled

Breast Neoplasms, Neoplasm, Residual

NCT04132505 2026-04-06

Binimetinib and Hydroxychloroquine in Treating Patients With KRAS Mutant Metastatic Pancreatic Cancer

Phase 1 Completed

34 enrolled

Phase EARLY_PHASE1 Recruiting

Pancreatic Neoplasms

NCT06408298 2026-02-04

HCQ in Resectable Localized Prostate Cancer

20 enrolled

Genitourinary

Resectable Localized Prostate Cancer

NCT04201457 2026-02-03

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Phase 1/2 Active not recruiting

57 enrolled

CNS

Glioma

NCT04524702 2026-01-23

Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer

Phase 2 Completed

10 enrolled 13 charts

Pancreatic Neoplasms

NCT06971744 2025-12-22

Autophagy Maintenance (AUTOMAIN)

Phase 2 Recruiting

38 enrolled

Gynecologic

Ovarian Neoplasms

NCT05843188 2025-12-09

Study of Hydroxychloroquine With FOLFIRI and Bevacizumab in DTP-high Metastatic Colorectal Cancer

155 enrolled

Colorectal Neoplasms

NCT00977470 2025-10-15

Erlotinib With or Without Hydroxychloroquine in Chemo-Naive Advanced NSCLC and (EGFR) Mutations

76 enrolled 12 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05221320 2025-09-25

Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) Malignancies

Phase 2 Terminated

47 enrolled 18 charts

Gastrointestinal Neoplasms, Neoplasms

NCT03037437 2025-09-04

Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer

Phase 2 Completed

64 enrolled

Liver Neoplasms

NCT04669197 2025-08-15

Study of Paclitaxel Protein Bound + Gemcitabine + Cisplatin + Hydrochloroquine as Treatment in Untreated Pancreas Cancer

19 enrolled

Untreated Resectable Pancreatic Adenocarcinoma

NCT01506973 2025-07-25

A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer

Phase 1/2 Completed

119 enrolled

Tumor-Agnostic

Adenocarcinoma

NCT03377179 2025-07-23

A Study of ABC294640 Alone and in Combination With HCQ Sulfate in the Treatment of Advanced Cholangiocarcinoma

Phase 2 Completed

65 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT03032406 2025-07-22

CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast Cancer

53 enrolled 12 charts

Phase 3 Not yet recruiting

Breast Neoplasms

NCT07061717 2025-07-11

Comparing Endocrine Therapy Combined With High-Dose Palbociclib and Hydroxychloroquine to Endocrine Therapy Combined With Standard-Dose Palbociclib for Hormone Receptor-Positive and HER2-Negative Advanced Breast Cancer

474 enrolled