NCT06899061 2026-03-27
Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib
AstraZeneca
Phase 1 Active not recruiting
Clinical Trials
13 trialsNCT07372625 2026-03-12
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
PMV Pharmaceuticals, Inc
Phase 1 Recruiting
NCT03006172 2026-03-11
To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Genentech, Inc.
Phase 1 Active not recruiting
NCT07459595 2026-03-10
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study
Combined Military Hospital Gujranwala
Phase 1 Not yet recruiting
NCT07399535 2026-02-10
PCOS
Jinnah Postgraduate Medical Centre
Phase 1 Recruiting
NCT02336087 2026-02-04
Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
City of Hope Medical Center
Phase 1 Active not recruiting
NCT06044025 2026-01-15
A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
University of Arkansas
Phase 1 Recruiting
NCT07098299 2025-11-06
Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
Barbara Ann Karmanos Cancer Institute
Phase 1 Recruiting
NCT03889795 2025-10-20
Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
University of Toledo
Phase 1 Active not recruiting
NCT05536037 2025-05-15
Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions
Thomas Jefferson University
Phase 1 Terminated
NCT01430351 2025-05-07
Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT03311308 2025-05-06
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma
University of Pittsburgh
Phase 1 Recruiting
NCT02339168 2025-05-01
Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer
University of California, Davis
Phase 1 Completed