Clinical Trials Browser

Endometrial Neoplasms

NCT07603505 2026-05-27

NAE-PCOS

Phase 1 Recruiting

116 enrolled

Infertility, Insulin Resistance, Metabolic Diseases, Polycystic Ovary Syndrome

NCT02186847 2026-05-22

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

Phase 2 Completed

170 enrolled 19 charts

Thoracic

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung

NCT05768139 2026-05-22

PIKALO-1

Phase 1/2 Recruiting

880 enrolled

BreastGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Breast Diseases, Breast Neoplasms, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Neoplasms, Neoplasms by Site, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Endometrial Neoplasms

Clinical Trials

ENDOLA

NAE-PCOS

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

PIKALO-1

Enhancing PCOS Management for Better Outcomes of Intracytoplasmic Sperm Injection

Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity

Inositol in Letrozol Resistant PCOS Women

COAST

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients

PNOC041

Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S

Met Med Can

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

SGLT2 Inhibitors in Treating Patients With PCOS

METLUNG

METCAP

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib

Morpheus-panBC

A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study

Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome

Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

SHK002

PCOS

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

PCOS

Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia

Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat Obesity

PCOS-COMBO (9)

Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy

Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS

Metformin and Nightly Fasting in Women With Early Breast Cancer

A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging

Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

Metformin to Mitigate Sequelae of Radioactive Iodine Treatment for Thyroid Cancers

REPAIR

PragMet

Effect of Metformin on Patients With Polycystic Ovary Syndrome