Announcements Trials
Browse Landscape

Phase

Phase 2 5Phase NA 1Phase 3 1

Status

Recruiting 3Completed 3Not yet recruiting 1

Sponsor Class

OTHER 7

Study Type

Interventional 7

Sponsor

Cancer Type

Head & Neck 2Breast 2Thoracic 1Other 1

Conditions

Head and Neck Neoplasms 2Breast Neoplasms 2Pentoxifylline, Cisplatin, Nephrotoxixcity 1Pain 1Osteoradionecrosis 1Mucositis 1Lymphedema 1Fibrosis 1Carcinoma, Non-Small-Cell Lung 1

Interventions

pembrolizumab 593Cyclophosphamide 539Magnetic Resonance Spectroscopy 527Radiotherapy 506Specimen Handling 504Nivolumab 406Cisplatin 370Carboplatin 360Biopsy 306Blood Specimen Collection 296Radiosurgery 284Paclitaxel 276Surveys and Questionnaires 269Standard of Care 267Gemcitabine 266fludarabine 261Dexamethasone 258Drug Therapy 256Bevacizumab 248venetoclax 247Oxaliplatin 206Rituximab 197Capecitabine 194Radiation 190Fluorouracil 186Ipilimumab 183durvalumab 181Doxorubicin 174atezolizumab 172Etoposide 171

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
OTHER × Pentoxifylline × 1 year × Clear all
NCT06634056 2026-03-04

P4-PACIFIC

University Health Network, Toronto

Phase 2 Not yet recruiting
150 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT05640817 2026-02-06

Nephroprotective Effect of Pentoxifylline Against Cisplatin in Patients With Head and Neck Cancer

Tanta University

Phase NA Completed
90 enrolled

Pentoxifylline, Cisplatin, Nephrotoxixcity

NCT06912763 2026-01-26

Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)

M.D. Anderson Cancer Center

Phase 2 Recruiting
250 enrolled
Head & Neck

Fibrosis, Head and Neck Neoplasms, Lymphedema

NCT06055257 2025-09-12

Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible

Sunnybrook Health Sciences Centre

Phase 3 Recruiting
24 enrolled
Head & Neck

Head and Neck Neoplasms, Osteoradionecrosis

NCT07137793 2025-08-22

PTX / BC

Tanta University

Phase 2 Recruiting
46 enrolled
Breast

Breast Neoplasms

NCT06186700 2025-07-28

Effect of Pentoxifylline on Preventing Chemotherapy-induced Toxicities in Patients With Breast Cancer

Mansoura University

Phase 2 Completed
100 enrolled
Other

Mucositis

NCT06087237 2025-06-26

The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery

Mansoura University

Phase 2 Completed
92 enrolled
Breast

Breast Neoplasms, Pain

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